This article refers to permanent shortening of muscles, tendons, or ligaments. For short-term contraction of muscles, see Muscle contraction. A muscle contracture is a permanent shortening of a muscle or joint. It is usually in response to prolonged hypertonic spasticity in a concentrated muscle area, such as is seen in the tightest muscles of people with conditions like spastic cerebral palsy. Contractures are essentially muscles or tendons that have remained too tight for too long, thus becoming shorter. They develop when these normally elastic tissues are replaced by inelastic tissues. This results in the shortening and hardening of these tissues, ultimately causing rigidity, joint deformities, and a total loss of movement around the joint. Most of the physical therapy, occupational therapy, and other exercise regimens targeted towards people with spasticity focuses on trying to prevent contractures from happening in the first place. However, research on sustained traction of connective tissue in approaches such as adaptive yoga has demonstrated that contracture can be reduced, at the same time that tendency toward spasticity is addressed.
Allergan, Inc.
https://thespotlyte.com/index.html
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Allergan, Inc. operated as a global healthcare company. It engaged in the development and commercialization of specialty pharmaceutical, medical device ,and over-the-counter products for the ophthalmic, neurological, medical aesthetics, medical dermatology, breast aesthetics, obesity intervention, urological, and other specialty markets. The company was founded by Gavin S. Herbert in 1950 and headquartered in Irvine, CA.
Over-the-counter
Dermatology
Botanical drug
Herb
Medical equipment
Dental Equipment
Corbus Pharmaceuticals, Inc.
http://www.corbuspharma.com
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JB Therapeutics is a clinical stage biopharmaceutical company developing the first new class of analgesic agents in two decades. Their lead compound, JBT-101, is a potent CB1 and CB2 agonist with demonstrated efficacy in several animal models of pain and inflammation. It has also completed a Phase II clinical study in chronic refractory neuropathic pain. JBT-101 is currently being developed as a potential disease modifying treatment for osteoarthritis. JBT-101 also represents a platform for combination with other anti-inflammatory and analgesic agents as well as various drug delivery strategies including ointment and gels, topical patches, and timed release formulations.
Dermatomyositis
Pharmacy and Therapeutics
Analgesic agents
Cannabidiol
Pharmacy
Drug
Medicine
Biopharmaceutical
Neuropathic pain
Agonist
Lead compound
Animal model
Osteoarthritis
Anti-inflammatory
Refractory
Inflammation
Glaxo Group Ltd.
https://www.gsk.com/en-gb
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Glaxo Group Ltd. operates through its subsidiary Glaxo Laboratories Ltd. that engages in the production of food products for infants such as Ostermilk, Complan, Casilan, Farex. Glaxo Group Ltd. was formerly known as Glaxo Laboratories Ltd. and changed its name to Glaxo Group Ltd. in 1962. The company is based in Brentford, United Kingdom. Glaxo Group Ltd. operates as a subsidiary of Glaxosmithkline plc.
Dynasplint Systems, Inc.
http://www.dynasplint.com
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Dynasplint Systems, Inc. provides bilateral spring loaded tensioning devices. Its systems are biomechanically point and counterforce systems. This design allows Dynasplint systems to closely mimic the therapists hands. The company was founded by George R. Hepburn in 1981 and is headquartered in Severna Park, MD.
Medical equipment
Splint device
Counterforce
Ajinomoto Co., Inc.
http://www.ajinomoto.co.jp
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Ajinomoto Co. is a global manufacturer of high-quality seasonings, processed foods, beverages, amino acids, pharmaceuticals and specialty chemicals. For many decades Ajinomoto Co. has contributed to food culture and human health through wide-ranging application of amino acid technologies. Today, the company is becoming increasingly involved with solutions for improved food resources, human health and global sustainability. Founded in 1909 and now operating in 26 countries, Ajinomoto Co. had net sales of JPY 1,197.3 billion (USD 15.1 billion) in fiscal 2011.
The Ajinomoto Group Standards of Business Conduct (hereinafter the "Standards of Conduct") describe the conduct that every member of the Ajinomoto Group must understand and practice every day in order to implement the Ajinomoto Group Philosophy in accordance with the Ajinomoto Group Way. The Standards of Conduct also represent the commitments made to all stakeholders by Ajinomoto Group companies.
Ajinomoto aim to be "a group of companies that contributes to human health globally" by continually creating unique value to benefit customers.
To become a global group of food companies centered on the world's No. 1 seasoning business.
To become a global group of aminoscience companies that contributes to humankind with the world's No. 1 amino acid technology.
To become a group of health-promoting companies with a scientific approach to good taste and health.
Seasoning
Amino acid
Food processing
Agriculture
Food industry
Starch
Sucralose
Aspartame
Fructose
Medicine
Artificial Sweetener
Sugar substitute
Saccharin
Neotame
Sorbitol
Spice
Acesulfame potassium
Xylitol
Herb
i2r Medical Ltd.
http://www.i2rmedical.com
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I2r Medical is developing of a wound healing device specifically for the treatment of diabetic foot and leg wounds at an early stage to prevent infection and subsequent complications including amputations.
Wound healing
Diabetic foot
Amputation
Complication
Allergan Sales LLC wholesales pharmaceutical products. It is a wholly-owned subsidiary of Allergan, Inc. The company is located in Englewood. CO
Medical equipment
Drug
Medicine
Arachnova Therapeutics Ltd.
Shaanxi Ruisheng Biological Technology Co. Ltd.
Shaanxi Ruisheng Biotechnology Co., Ltd., established on 2008-03-12, Business scope includes general items:Production of Class I Medical Devices;Sales of Class I Medical Devices;Sales of Class II Medical Devices;R&D and application of cell technology;Technical Services,technology development,technical consulting,Technology Exchange,technology transfer,Technology Promotion;Sales of hygiene products and single-use medical products;Cosmetics Wholesale;Cosmetics Retail;Technology Import and Export.(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license)licensed items:Production of Class II Medical Devices;Production of Class III Medical Devices;Class III medical device business;Production of hygiene products and single-use medical products.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments,Specific business projects are subject to approval results)
DexCom, Inc. is a medical device manufacturing company, which engages in the design, development and commercialization of glucose monitoring systems for ambulatory use by people with diabetes. Its products include Dexcom G6 CGM System, DexCom G6 CGM System for Medicare, Software and Mobile apps. The company was founded by John F. Burd on May 1, 1999 and is headquartered in San Diego, CA.
Medical equipment
Diabetes management
Blood glucose monitoring
Glucose sensors
Glucose sensing
Insulin pump
Insulin pen
Blood glucose test strip
Wearable technology
Snf3
Endocrinology
Insulin aspart
Biocompatible material
Insulin
Bionics
Smartwatch
Avionics
ARCH Development Corp.
http://www.archdevelopment.org
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Part of The University of Chicago, ARCH Development Corp. is an American company. The firm provides job training and housing development services. Duane Gautier is currently the CEO of the firm.
Part of Orthofix Medical, Inc., AMEI Technologies, Inc. is a company headquartered in the United States providing investment services.
Applied Research Systems ARS Holding NV
Smith + Nephew, Inc.
http://www.smith-nephew.com
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Smith & Nephew PLC designs, manufactures and markets orthopedic devices, sports medicine and ENT technologies, and wound-care solutions. Slightly more than 40% of the U.K.-based firm's revenue comes from orthopedic products, and another 30% is a sports medicine and ENT. The remaining 27% of revenue is from the advanced wound therapy segment. Roughly half of Smith & Nephew's total revenue comes from the United States, just over 30% is from other developed markets, and emerging markets account for the remainder.
Kowa Co., Ltd. engages in trading of textiles, machinery, and construction materials. The company also manufactures and sells medicines, medical equipment, and energy saving products. It operates through the following business divisions: Pharmaceutical, Medical Device, Foods, General Trading, Lifestyle Business, and Hospitality. The company was founded on December 25, 1894 and is headquartered in Nagoya, Japan.
Medicine
Medical equipment
Textile
Lifestyle business
Refractive error
Retinopathy
Macular degeneration
Glaucoma
Optometry
Intraocular lens
Slit lamp
Astigmatism
Fundus camera
Retinal detachment
Cataract surgery
Cornea
Blindness
Ophthalmology
Refractive surgery
Optical coherence tomography
National Rehabilitation Center
National Rehabilitation Center is a Korean public health agency that oversees treatment, rehabilitation research, education and training.
Merck Serono SA operates as a holding company in the pharmaceutical field. It engages in the research, development, manufacture, and distribution of therapeutic products for the treatment of human diseases. The company was founded on May 21, 1987 and is headquartered in Coinsins, Switzerland.
Biology
Fertility
Medicine
Multiple sclerosis
Fertility drugs
Reproductive cycle
Drug
Head and neck cancer
Biosimilar
Colorectal cancer
Reproductive health
Endocrinology
Therapeutic Area
Biomedicine
Biotechnology
Oncology
Gene delivery
Injector
Luteinizing hormone
Guanhao Biotech Co., Ltd.
http://www.guanhaobio.com
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Grandhope Biotech Co., Ltd, a bio-tech company, develops, manufactures, and markets regenerative medical devices for the treatment of damaged tissue and organs in China. The company offers GrandNeuro membrane, an artificial dura patch for dura repairing; and NormalGEN, a type of biological dura repair patch manufactured from animal tissue used for the closure of dura mater during neurosurgery. It also provides ThormalGEN, a biological surgical patch manufactured from animal tissue for surgical repairs; and DermalGEN, a wound dressing product for use on burns, scalds, and wounds due to skin loss or trauma.
Medical equipment
Breast reconstruction
Hernia repair
Soft tissue repair
Stem cell
Arthroscopy
Laparoscopy
Cell
Multipotent cell
Autologous chondrocyte implantation
Cell bank
Cartilage
Antigen
Human body
Regenerative medicine
Incubator
Advance Biofactures Corp.
Part of Endo International Plc, Advance Biofactures Corp. is a company headquartered in the United States focused on pharmaceutical preparations.
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