LDR Medical SAS specializes in the design, production and marketing of surgical implants. The firm specializes in orthopedics and neurosurgery. Its products include cervical and thoracolumbar. The company was founded by Christophe Lavigne, Herve Dinville and Patrick Richard in 2000 and is headquartered in Troyes, France.

DePuy Mitek LLC develops, manufactures, and supplies medical devices. Its products include pins, fasteners, suture anchors, and screws. It also offers surgical solutions. It has operations in Raynham, Massachusetts, Neuchatel, Switzerland, and France. The company was founded by Jim Nicholson and Arthur Collias in 1985 and is headquartered in Raynham, MA.

ColBar LifeScience Ltd. develops, manufactures, and commercializes bio-surgical products.

ISTO Technologies, Inc., an orthobiologics company, develops biologic products to regenerate and restore function to damaged cartilage and bone. It offers InQu, a resorbable bone graft extender and substitute; NuQu, a cell-based injectable therapy for disc regeneration; and DeNovo ET, an engineered cartilage implant for the repair and regeneration of knee cartilage. The company provides its products through distributors. ISTO Technologies, Inc. was founded in 1997 and is based in St. Louis, Missouri.

Mochida Pharmaceutical is a drug manufacturing company. Their pharmaceutical business aims to develop and market a broad spectrum of innovative new drugs. They also offer creates skin care products for the general public, and these are supplied through pharmacies, and drugstores.

Mariel Therapeutics, Inc., part of Ember Therapeutics, Inc., is an American company located in New York, NY, that provides treatment for osteoarthritis and kidney fibrosis diseases. It was acquired by Ember Therapeutics, Inc. on March 12, 2015.

ReGen Biologics, Inc. designs, develops, manufactures, and markets medical devices for the repair and generation of soft tissue in humans, primarily for orthopedic applications. The company’s proprietary collagen matrix technology includes applications in orthopedics, general surgery, spine, cardiovascular, and drug delivery. Its products include Menaflex collagen meniscus implant device, for use in surgical procedures for the reinforcement and repair of soft tissue injuries of the medial meniscus; and SharpShooter Tissue Repair System, an instrument that allows surgeons to place needles in hard-to-reach locations of the meniscus. The company sells its products in the United States, the European Union, the Republic of South Africa, Canada, Australia, Chile, and Japan. ReGen Biologics, Inc. was founded in 1987 and is headquartered in Hackensack, New Jersey. On April 8, 2011, ReGen Biologics, Inc. filed a voluntary petition for reorganization under Chapter 11 in the U.S. Bankruptcy Court for the District of Delaware. The plan was later approved as Chapter 11 liquidation on October 14, 2011.

Spineology provides anatomy-conserving spine surgery technology solutions. It offers pedicular fixation products, such as Palisade, threshold, and fortress pedicular fixation; Biologics products, such as Essence viable amnion matrix, Blockade amniotic protective barrier, Incite DBM strips, and Incite cortical fibers; and Interbody products, such as the Duo systems, Elite expandable, Rampart one, and Rampart T interbody fusion products. Spineology also offers capture facet fixation, VIA spinous process fixation, Medius retractor system, SOAR retractor system, ProMap EMG nagivation systems, and OptiMesh graft containment. Stephan Kuslich founded it in 1996, with its headquarters in St. Paul in Minnesota.

Disc Dynamics is a healthcare company. They design and develop medical products. The Company offers surgical alternatives for the treatment of lower back problems and disc diseases. It offers DASCOR Disc arthroplasty system, a catheter-based minimally invasive nucleus replacement technology for the treatment of degenerated lumbar discs. Disc Dynamics was founded by Jeffrey Felt in 2000 and is headquartered in Eden Prairie, Minnesota.

Founded in January of 2009 in Minnetonka, Minnesota, ABS Corporation designs and develops minimally invasive technology focused on relieving pain in the knee. Two medial knee implant systems have been developed: The PEEK Mobility® Medial Knee Implant and the OrthoGlide® Medial Knee Implant. The PEEK Mobility Medial Knee Implant has received CE Mark approval. The OrthoGlide Medial Knee Implant has received FDA clearance and CE Mark approval.

Stryker Corp. is a medical technology company, which engages in the provision of innovative products and services that help improve patient and healthcare outcomes. It operates under the MedSurg and Neurotechnology, and Orthopaedics and Spine segments. The MedSurg and Neurotechnology segment includes surgical equipment and navigation systems, endoscopic and communications systems, patient handling, emergency medical equipment, intensive care disposable products, clinical communication, workflow solutions, products for the treatment of acute ischemic and hemorrhagic stroke, traditional brain, and open skull based surgical procedures, orthobiologic, and biosurgery. The Orthopaedics and Spine segment focuses on implants used in hip and knee joint replacements and trauma and extremity surgeries, and cervical, thoracolumbar, and interbody systems used in spinal injury, deformity, and degenerative therapies. The company was founded by Homer H. Stryker in 1941 and is headquartered in Kalamazoo, MI.

Peking University Third Hospital is a private company headquartered in Beijing, China, that operates as a clinic.

DePuy Products, Inc., part of Johnson & Johnson, is a company headquartered in the United States. The firm manufactures and distributes orthopaedic devices.

UAB Research Foundation (doing business as UABRF), a subsidiary of The University of Alabama System, is a company headquartered in Birmingham, AL. The firm engages in identify, assess, and market commercially viable technology developed at The University of Alabama at Birmingham.

Anika Therapeutics Srl, part of Anika Therapeutics, Inc., is an Italian company located in Padua that provides hyaluronic acid-based products in several therapeutic areas including for the regeneration of connective and structural tissues damaged by injuries, aging or degenerative diseases. On December 31, 2009 Anika Therapeutics, Inc. acquired Anika Therapeutics Srl from Fidia Farmaceutici SpA for $33.87 million.

DePuy Synthes Products, Inc. develops and markets medical products. It offers distal volar Radius, which is designed to treat distal radius fractures, dorsal endoplate, an invasive dorsal nail plate that provides fixed angle support and intramedullary locked fixation with a duplicate and reproducible surgical procedure, spatial subchondral support plate, which is used to treat proximal humeral fractures and Small Bone Fixation System, a percutaneous locked intramedullary nail system for metacarpals and the phalanges. The company was founded on June 22, 2004 and is headquartered in Wilmington, DE.

K2M Group Holdings, Inc. (K2M) is a global medical device company focused on designing, developing and commercializing spine technologies and techniques. Its spine products are used by spine surgeons to treat some of the most difficult and challenging spinal pathologies, such as deformity (primarily scoliosis), trauma and tumor. Its products consist of implants, disposables and instruments which are marketed and sold primarily to hospitals for use by spine surgeons. In addition to its current product portfolio, it continue to invest in the design, development and commercialization of new solutions for unmet clinical needs in the complex spine and MIS markets by its product development process. The Company market and sell its products in the United States and 28 other countries. The Company’s products include Complex Spine, Minimally Invasive Spine and Degenerative Spine. The Company’s technologies include MESA, Rail 4D, Deformity Cricket, SERENGETI, RAVINE, EVEREST and tifix.