Astute Medical is dedicated to improving the diagnosis of high-risk medical conditions and diseases through the identification and validation of protein biomarkers that can serve as the basis for novel diagnostic tests. The Company's focus is on community and hospital-acquired acute conditions that require rapid diagnosis and risk assessment. The company's current areas of interest include abdominal pain, acute coronary syndromes, cerebrovascular injury, kidney injury and sepsis. Founded in 2007, the company is led by Christopher Hibberd and Paul McPherson, former members of the management at Biosite Incorporated, a leading diagnostics company acquired by Inverness Medical Innovations in 2007 for $1.7 billion. Hibberd served at Biosite for 10 years, most recently as Senior Vice President Corporate Development. Dr. McPherson was at Biosite for 14 years, most recently as Vice President Research and Development.

Roche Diagnostics GmbH, part of Roche Holding AG, is a company headquartered in Mannheim, Germany, involved in laboratory analytical instruments. Andreas Schmitz and Claus Haberda are the current co-CEOs of the firm. On January 01, 1999 Roche Holding AG acquired Roche Diagnostics GmbH.

Jiangsu Yangxin Biopharmaceutical Co., Ltd., established on 2013-04-28, Business scope includes biomedicine,Technology development of cosmetics,technology transfer,Technical consulting and related technical services;Production and sales of medical devices;Food wholesale and retail;cosmetic,Purchasing and selling of chemical raw materials and products;Self-operated and agent import and export business of various commodities and technologies.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments)

F. Hoffmann-La Roche Ltd. manufactures pharmaceutical products. It offers pharmaceutical drugs, pharmaceutical instruments, and diagnostics solutions. The company was founded by Fritz Hoffmann-La Roche on October 1, 1896 and is headquartered in Basel, Switzerland.

MediGene AG is a biotechnology company, which engages in developing innovative, complementary treatment platforms that target various types and stages of cancer. It focuses on the development of personalized T-cell based immunotherapies. It operates through the Immunotherapies and Other products segments. The company was founded by Ernst Ludwig Winnacker and Horst Domdey in June 1994 and is headquartered in Martinsried, Germany.

Genematrix is developing new diagnostic products for various diseases by developing a globally competitive core platform technologies in the field of molecular diagnostics, which is attracting attention as a high-technology in the line of biotechnology. The Molecular Diagnostic market has high growth rates among in-vitro diagnostics markets and is a high value-added industry that is highly dependent on advanced countries since global companies prevailed the most core technologies. Genematrix, since the beginning of the company, has developed its own technologies that is globally competitive in the field of molecular diagnostics through joint research with domestic and international companies and research institutes.

Roche Diagnostics Corp. develops and manufactures diagnostic products. It offers anticoagulation management, blood gas and electrolytes, cholesterol and urinalysis products. The firm provides a broad portfolio of tools that help healthcare providers in the prevention, diagnosis and management of diseases like HPV, HIV, heart failure and diabetes, as well as other medical conditions, such as fertility and blood coagulation. Its products and services uses by researchers, physicians, patients, hospitals and laboratories worldwide. The company was founded in 1964 by Willard Eason and is headquartered in Indianapolis, IN.

Roche Diagnostics Operations, Inc. provides healthcare services. It offers commercial physical and biological research and development. The company is headquartered in Indianapolis, IN.

Shenzhen Airui Biotechnology Co., Ltd., established on 2007-01-09, Business scope includes general business items:Biotechnology,biological products,Bioassay Reagents,Nutrients,Research and development of beauty cosmetics(Does not include production and processing),domestic business,Material supply and marketing industry.(None of the above is legal,Administrative regulations,The State Council decides to specify items that require pre-approval and prohibition),The licensing program is:

Hangzhou Xianzhi Biotechnology Co., Ltd., established on 2009-05-07, Business scope includes biotechnology,biological products,Research and Development of Biological Instruments,consultation service,Technical service and achievement transfer;Wholesale and sales:biological products,biological instrument;Production and processing:bioengineering materials,Biological Reagent Raw Materials; (law,Except for projects prohibited by administrative regulations and involving pre-approval);Import and export of goods and technology(Except for goods and technologies that are restricted or prohibited from import and export by the state).(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments)

Chongqing Yeweiji Biotechnology Group Co., Ltd, established on 2010-10-21, Business scope includes licensed projects:Production of Class III Medical Devices;Class III medical device business;Production of Class II Medical Devices;Drug Wholesale;pharmaceutical production;Import and export of goods managed by state trade;Cosmetic production.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments,The specific business items are subject to the approval documents or licenses of relevant departments)General project:Medical Research and Experimental Development;Technical Services,technology development,technical consulting,Technology Exchange,technology transfer,Technology Promotion;Sales of Class II Medical Devices;Sales of Class I Medical Devices;Production of Class I Medical Devices;Manufacturing of experimental analysis instruments;Cosmetics Retail;Cosmetics Wholesale.(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license)

Reigncom has technology innovation projects and production, learning, and research projects funded by STCSM, STCMD, and funds and is engaged in the research, development, manufacturing, and distribution of diagnostic medical devices, IVD reagent kits, and related services.

Shenzhen Kangmei Biotechnology Co. Ltd. manufactures surgical and medical instruments. It offers colloidal gold reagents, clinical biochemical reagents, nuclein acid purification reagents, diagnostic and analytical instruments, ELISA, and PCR kits. The firm also offers raw material for bio-engineering and biotech products; medical ultrasonic equipment, clinical laboratory testing products, and examination equipment; clinical diagnostic products; and raw materials for biological products. The company was founded in 2000 and is headquartered in Shenzhen, China.

Nanjing Norman Biological Technology Co., Ltd is dedicated to R&D and manufacturing of automated chemiluminescence system. Founded in 2008, Norman biological has been upholding the idea that R&D shapes future ,and concentration determines success. Ever since the beginning, Norman has been focusing on developing and manufacturing chemiluminescence instruments and reagents. Norman’s manufacture center is located in the Yuhua District and owns an over 2,000m2 GMP-approved clean workshop. The R&D base, which is over 2,000m2 , is located in state-level new Jiangbei district. Now there are over 100 R&D engineers, 40% of which hold a PhD or master’s degree.

Beijing Strong Biotechnologies, Inc. engages in the research and development, production, and sale of in-vitro diagnostics (IVD) products. It offers biochemical diagnostic reagents, tumor pathological detection reagents, biochemical detection system, blood coagulation detection system, and immunopathological staining system. The company was founded by Zuo Jun Zou and Xi Liu on March 29, 2001 and is headquartered in Beijing, China.

Nanjing Botian Kezhi Biotechnology Co., Ltd., established on 2006-08-07, Business scope includes medical device production(Operate according to the scope listed in the license);Research and development of biological products,Production,Sales and technical service;Sales of building materials;Research and development of environmental protection equipment,Production,Sales,Install,Technical Services.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments)

Hongkui Biological (China) Co., Ltd., established on 2014-06-19, Business scope includes general items:Production of Class I Medical Devices;Sales of Class I Medical Devices;Sales of Class II Medical Devices;Office Supplies Sales;Sales of daily chemical products;Manufacturing of daily chemical products;General merchandise sales;Engineering and Technology Research and Experimental Development;Engineering Management Services.(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license)licensed items:Production of Class II Medical Devices;Class III medical device business;Production of Class III Medical Devices;Various construction activities;Engineering cost consulting business;construction professional work;Construction labor subcontracting.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments,The specific business items are subject to the approval documents or licenses of relevant departments)

Randox Laboratories Ltd. provides clinical diagnostic solutions to laboratories. It develops, manufactures and markets high quality diagnostic reagents and equipment for laboratory medicine. The firm's products include Biochip Array Technology, clinical chemistry analyzers and reagents, quality control materials and schemes and an extensive life science portfolio. The company was founded by Peter FitzGerald in April 1982 and is headquartered in Crumlin, the United Kingdom.