Astute Medical is dedicated to improving the diagnosis of high-risk medical conditions and diseases through the identification and validation of protein biomarkers that can serve as the basis for novel diagnostic tests. The Company's focus is on community and hospital-acquired acute conditions that require rapid diagnosis and risk assessment. The company's current areas of interest include abdominal pain, acute coronary syndromes, cerebrovascular injury, kidney injury and sepsis. Founded in 2007, the company is led by Christopher Hibberd and Paul McPherson, former members of the management at Biosite Incorporated, a leading diagnostics company acquired by Inverness Medical Innovations in 2007 for $1.7 billion. Hibberd served at Biosite for 10 years, most recently as Senior Vice President Corporate Development. Dr. McPherson was at Biosite for 14 years, most recently as Vice President Research and Development.

Roche Diagnostics GmbH, part of Roche Holding AG, is a company headquartered in Mannheim, Germany, involved in laboratory analytical instruments. Andreas Schmitz and Claus Haberda are the current co-CEOs of the firm. On January 01, 1999 Roche Holding AG acquired Roche Diagnostics GmbH.

Dongguan Pengzhi Biotechnology Co., Ltd., established on 2016-08-22, Business scope includes biological products,R&D of medical devices,Production,Sales and technology transfer,Technical Services;Sales:Chemical Products(Free of Hazardous Chemicals);Import and export,Technology Import and Export.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments)

Nanjing Botian Kezhi Biotechnology Co., Ltd., established on 2006-08-07, Business scope includes medical device production(Operate according to the scope listed in the license);Research and development of biological products,Production,Sales and technical service;Sales of building materials;Research and development of environmental protection equipment,Production,Sales,Install,Technical Services.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments)

Genematrix is developing new diagnostic products for various diseases by developing a globally competitive core platform technologies in the field of molecular diagnostics, which is attracting attention as a high-technology in the line of biotechnology. The Molecular Diagnostic market has high growth rates among in-vitro diagnostics markets and is a high value-added industry that is highly dependent on advanced countries since global companies prevailed the most core technologies. Genematrix, since the beginning of the company, has developed its own technologies that is globally competitive in the field of molecular diagnostics through joint research with domestic and international companies and research institutes.

F. Hoffmann-La Roche Ltd. manufactures pharmaceutical products. It offers pharmaceutical drugs, pharmaceutical instruments, and diagnostics solutions. The company was founded by Fritz Hoffmann-La Roche on October 1, 1896 and is headquartered in Basel, Switzerland.

Roche Diagnostics Corp. develops and manufactures diagnostic products. It offers anticoagulation management, blood gas and electrolytes, cholesterol and urinalysis products. The firm provides a broad portfolio of tools that help healthcare providers in the prevention, diagnosis and management of diseases like HPV, HIV, heart failure and diabetes, as well as other medical conditions, such as fertility and blood coagulation. Its products and services uses by researchers, physicians, patients, hospitals and laboratories worldwide. The company was founded in 1964 by Willard Eason and is headquartered in Indianapolis, IN.

Shenzhen Airui Biotechnology Co., Ltd., established on 2007-01-09, Business scope includes general business items:Biotechnology,biological products,Bioassay Reagents,Nutrients,Research and development of beauty cosmetics(Does not include production and processing),domestic business,Material supply and marketing industry.(None of the above is legal,Administrative regulations,The State Council decides to specify items that require pre-approval and prohibition),The licensing program is:

Jiangsu Yangxin Biopharmaceutical Co., Ltd., established on 2013-04-28, Business scope includes biomedicine,Technology development of cosmetics,technology transfer,Technical consulting and related technical services;Production and sales of medical devices;Food wholesale and retail;cosmetic,Purchasing and selling of chemical raw materials and products;Self-operated and agent import and export business of various commodities and technologies.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments)

Szybio is engaged in the research and development, production, and sales of in vitro diagnostic reagents for clinical medicine. Their products and services include biochemical diagnostic reagent products, molecular diagnostic reagents, diagnostic testing-related equipment focusing on latex-enhanced immune turbidimetric technology products, and more.

Hangzhou Xianzhi Biotechnology Co., Ltd., established on 2009-05-07, Business scope includes biotechnology,biological products,Research and Development of Biological Instruments,consultation service,Technical service and achievement transfer;Wholesale and sales:biological products,biological instrument;Production and processing:bioengineering materials,Biological Reagent Raw Materials; (law,Except for projects prohibited by administrative regulations and involving pre-approval);Import and export of goods and technology(Except for goods and technologies that are restricted or prohibited from import and export by the state).(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments)

Roche Diagnostics Operations, Inc. provides healthcare services. It offers commercial physical and biological research and development. The company is headquartered in Indianapolis, IN.

Reigncom has technology innovation projects and production, learning, and research projects funded by STCSM, STCMD, and funds and is engaged in the research, development, manufacturing, and distribution of diagnostic medical devices, IVD reagent kits, and related services.

Avike Biotechnology Co., Ltd., established on 2016-01-18, Business scope includes biological products,Pharmaceutical Intermediates,Research and development of diagnostic reagents,technology transfer,medical instruments,Production of medical supplies,Wholesale and retail,drug development,manufacture,Import and export business of goods and technology.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments)

Beijing Strong Biotechnologies, Inc. engages in the research and development, production, and sale of in-vitro diagnostics (IVD) products. It offers biochemical diagnostic reagents, tumor pathological detection reagents, biochemical detection system, blood coagulation detection system, and immunopathological staining system. The company was founded by Zuo Jun Zou and Xi Liu on March 29, 2001 and is headquartered in Beijing, China.

Hongkui Biological (China) Co., Ltd., established on 2014-06-19, Business scope includes general items:Production of Class I Medical Devices;Sales of Class I Medical Devices;Sales of Class II Medical Devices;Office Supplies Sales;Sales of daily chemical products;Manufacturing of daily chemical products;General merchandise sales;Engineering and Technology Research and Experimental Development;Engineering Management Services.(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license)licensed items:Production of Class II Medical Devices;Class III medical device business;Production of Class III Medical Devices;Various construction activities;Engineering cost consulting business;construction professional work;Construction labor subcontracting.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments,The specific business items are subject to the approval documents or licenses of relevant departments)

Guangzhou Tianbao Songyuan Biotechnology Development Co., Ltd., established on 2007-05-31, Business scope includes biotechnology development services;Chemical Engineering Research Services;Commodity retail trade(Except for licensed and approved products);Commodity wholesale trade(Except for licensed and approved products);Import and export(Excluding franchised products);Technology Import and Export;medical diagnosis,Monitoring and treatment equipment manufacturing

Chongqing Zunsheng Donglin Medical Technology Co., Ltd., established on 2018-12-28, Business scope includes licensed projects:Production of sterile equipment,Disinfectant production,Production of disinfection products for the prevention and control of infectious diseases,Production of Class III Medical Devices,Production of Class II Medical Devices,Class III medical device business,Production of hygiene products and single-use medical products,Production of protective equipment for medical personnel(Class II medical device),Production of formula food for special medical purpose,food production,Health food production,food business,Health food sales,Sales of formula food for special medical purposes(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments,The specific business items are subject to the approval documents or licenses of relevant departments)General project:Engaged in technology development in the field of medical technology,hospital management,Medical Information Consultation(Does not include diagnosis and treatment),Medical equipment maintenance and technical consultation,Business Management Consulting,Business Consulting,Conference planning,Corporate Image Planning,Medical equipment rental,Disinfectant sales,Professional cleaning,to clean,Disinfection service,Wholesale of Class I Medical Devices,Wholesale of Class II Medical Devices,Production of protective equipment for medical personnel(Ι class medical device),Production of Class I Medical Devices,Sales of hygiene products and single-use medical products,Retailing of Class I Medical Devices,Retailing of Class II Medical Devices,Medical equipment rental,Traditional Chinese Medicine Health Care Services(non-medical),Nursing facility services(Does not include medical services),Maternal and infant life care(Does not include medical services),Retailing of protective equipment for healthcare workers,Wholesale of protective equipment for medical staff,Medical Mask Retail,Wholesale medical masks,Special Equipment Repair,Domestic trade agent,software development,Health Consulting Services(Does not include medical services),Manufacturing of computer software, hardware and peripheral equipment,Manufacturing of special equipment(Manufacture of licensed professional equipment not included),raw nuts,Dried Fruit Wholesale,Conference and Exhibition Services,Etiquette service,Computer and Office Equipment Repair,Machinery sales,Electrical Equipment Sales,Sales of building materials,Wholesale of hardware products,Sales of electronic components and electromechanical components(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license)

Jiangsu Dajun Biotechnology Co., Ltd., established on 2014-06-04, Business scope includes biotechnology,Technology development of medical devices,technical consulting,Technical Services,technology transfer;Manufacturing and sales of medical devices;biochemical enzyme,antigen,Sales of antibodies and other chemical products(Free of hazardous chemicals and drugs);Food Safety Testing Biological Reagents(Free of Hazardous Chemicals)and instruments(Without measuring instruments)technology development,production and sales.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments)