Edwards Lifesciences Corp. engages in patient-focused medical innovations for heart disease and critical care monitoring. Its products are categorized into four main areas: Transcatheter Aortic Valve Replacement, Transcatheter Mitral and Tricuspid Therapies, Surgical Structural Heart, and Critical Care. It operates through the following geographical segments: United States, Europe, Japan, and Rest of World. The company was founded by Miles Lowell Edwards in 1958 and is headquartered in Irvine, CA.

Cardiac Pacemakers, Inc.(CPI), doing business as Guidant Cardiac Rhythm Management, manufactured implantable cardiac rhythm management devices, such as pacemakers and defibrillators. It also sold insulin pumps controlled by microprocessors and various equipments to regulate heart rhythm. In addition, Cardiac Pacemakers, Inc. developed therapies for the treatment of irregular heartbeats. The company was founded in 1971 and is based in St. Paul, Minnesota. Cardiac Pacemakers, Inc. operates as a subsidiary of Boston Scientific Corporation.

Medtronic, Inc. operates as a medical technology company. It offers implantable cardiac pacemakers, eternal defibrillators, inferior turbinate surgery products, and continuous glucose monitoring device. The company was founded by Earl E. Bakken and Palmer J. Hermundslie on April 29, 1949 and is headquartered in Minneapolis, MN.

Sanofi is a global healthcare company. Among their duties are researching disease causes, determining starting points for drug treatment, developing drugs, producing active ingredients, and delivering finished drugs and active ingredients. Specialists in vaccines, rare diseases, rare blood disorders, neurology, immunology, oncology, diabetes, cardiovascular diseases, and consumer healthcare.

St. Jude Medical, Inc. was an American global medical device company headquartered in Little Canada, Minnesota, U.S., a suburb of Saint Paul. The company had more than 20 principal operations and manufacturing facilities worldwide with products sold in more than 100 countries. Its major markets include the United States, Europe, Latin America and Asia-Pacific. The company was named after Jude the Apostle, the patron saint of lost causes.

Harmony Development Group is a heart-focused MedTech company. It works within the ventricle, functioning as an integrated systolic assist system that leverages the native energy of the heart. Their therapies work by aiding and supporting the diseased ventricle, restoring its natural shape, pressure, and flow.

Calon Cardio-Technology Ltd develops implantable micro blood pumps for the treatment of chronic heart failure. It offers MiniVAD, a miniature implantable blood pump that is implanted into the left ventricle of the failing heart to help provide blood supply to the body, alleviate the debilitating symptoms of heart failure, and slow or halt heart failure disease progression. The company’s products also comprise MicroVAD, a miniaturized pump for the earlier treatment of patients progressing through the spectrum of advancing heart failure; and CathVAD, a catheter delivered micro-pump for the treatment of acute heart failure.

Biotronik (Biotronik SE & Co. KG; Biotronik Worldwide) is a privately held multinational biomedical technology company headquartered in Berlin, Germany. The company offers complete solutions for diagnosis, treatment, and therapy support in the areas of cardiac rhythm management, electrophysiology and vascular intervention. In the area of cardiac rhythm management, Biotronik Home Monitoring® uses telemonitoring technology to provide doctors with up-to-date information for implant patients.

The University of California is the nation's best public university system, delivering top-notch research and innovation to California (and the world).

InControl, Inc., a subsidiary of DAIKIN INDUSTRIES Ltd., is an American company located in Redmond, WA. The firm manufactures heating, ventilation and air conditioning equipment. It was founded in 1990 by Michel E. Lussier, Clifton A. Alferness, Kurt C. Wheeler and John M. Adams. InControl, Inc. was acquired by AirReps LLC from Boston Scientific Corp. on July 10, 2023.

Eclipse Surgical Technologies, Inc. develops and distributes laser-based surgical products and disposable fiber-optic accessories for the treatment of advanced cardiovascular disease. The Company's emphasis is on the development and manufacture of products used for transmyocardial revascularization (TMR) and percutaneous myocardial channeling (PMC), which are cardiovascular procedures. Eclipse Surgical Technologies, markets its products for sale in the United States, Europe and Asia. Eclipse Surgical Technologies is located in Foothill Ranch, CA.

Abiomed is a provider of mechanical circulatory support devices and offers a continuum of care to heart failure patients. The Company develops, manufacture and market products that is designed to enable the heart to rest, heal and recover by improving blood flow and/or performing the pumping function of the heart. The Company's products are used in the cardiac catheterization lab (cath lab) by interventional cardiologists and in the heart surgery suite by heart surgeons for patients who are in need of hemodynamic support prophylactically or emergently before, during or after angioplasty or heart surgery procedures.

Part of Abbott Laboratories, St. Jude Medical, Atrial Fibrillation Division, Inc. is an American company that manufactures and markets medical devices.

Part of BIOTRONIK SE & Co. KG, Biotronik AG is a Swiss company located in Bulach that manufactures devices for vascular intervention and electrotherapy of heart.\nThe company says this about itself: BIOTRONIK is a leading medical device company that has been developing trusted and innovative cardiovascular and endovascular solutions for more than 50 years. Driven by a purpose to perfectly match technology with the human body, BIOTRONIK innovations deliver care that saves and improves the lives of millions diagnosed with heart and blood vessel diseases every year. BIOTRONIK is headquartered in Berlin, Germany, and represented in over 100 countries.

Part of Abbott Laboratories, Daig Corp. is an American company located in Hopkins, MN. The firm manufactures specialty catheters. St. Jude Medical LLC, now part of Abbott Laboratories acquired Daig Corp. on May 31, 1996 for $439.60 million.

Pacesetter, Inc., a subsidiary of Abbott Laboratories, is a company headquartered in the United States that manufactures, and distributes cardiovascular and implantable neuro stimulation medical devices.

Develops and markets complex devices for treating malfunctions of the heart

Twelve, Inc. is a holding company, which engages in the operation as an investment fund for a medical device incubator. It specializes on funding and developing medical device inventions. The company focuses on medical and biotech ventures. The company was founded in 2009 and is headquartered in Redwood City, CA.

CMI Holding Company, Inc., a medical device company, develops and markets cardiac surgeon devices. It offers Surgical Ventricular Restoration (SVR) System, which utilizes the Mannequin device to treat patients suffering from ischemic heart failures. The company also offers beating heart surgical products, such as Minimally Invasive Cardiac Surgery Systems, vacuum stabilization products, apical positioners, and blower misters; Viper II Vacuum Stabilizer Systems, Viper Vacuum Stabilizer Systems, and TRIPOD, which are beating heart stabilization systems; and Sof-Flo Atraumatic Coronary Artery Shunts and Bulb Tip Intracoronary Shunts, which minimizes trauma and facilitates coronary artery insertion and removal. In addition, it offers stroke prevention systems, such as TRIUMPH Soft Occlusion Aortic Cannula System that is used in the management of patients with highly fragile or heavily calcified aortas. Further, the company provides SVR procedure training for surgeons in the United States and internationally. CMI Holding Company, Inc. was formerly known as Chase Medical, Inc. The company was founded in 1995 and is based in Richardson, Texas.

NewCardio, Inc. is a cardiac diagnostic technology provider, which focuses on the research, development, and commercialization of proprietary software platform technology solutions for the non-invasive diagnosis and monitoring of cardiovascular diseases, as well as the cardiac safety assessment of drugs under development. It engages in the development of three solutions through a 3D platform technology, which includes, QTinno, an automated cardiac safety solution that streamlines the process for meeting the early phase cardiac safety analysis, CardioBip, a wireless transtelephonic system which engages in delivering remote diagnosis and review of patients with chronic cardiac conditions, and my3KG, a software application developed to assess cardiac electrical activity in time and space. The company was founded on September 2, 2003 and is headquartered in Princeton, NJ.