Smith & Nephew PLC designs, manufactures and markets orthopedic devices, sports medicine and ENT technologies, and wound-care solutions. Slightly more than 40% of the U.K.-based firm's revenue comes from orthopedic products, and another 30% is a sports medicine and ENT. The remaining 27% of revenue is from the advanced wound therapy segment. Roughly half of Smith & Nephew's total revenue comes from the United States, just over 30% is from other developed markets, and emerging markets account for the remainder.

Part of Zimmer Biomet Holdings, Inc., Zimmer Technology, Inc. is an American company involved in surgical and medical instruments and apparatus.

Ascension Orthopedics, Inc. designs, develops and markets orthopedic implants and devices. The company was founded by Jerome J. Klawitter in 1996 and is headquartered in Overland Park, KS.

Part of Smith & Nephew plc, Smith & Nephew Orthopaedics GmbH is a company headquartered in Tuttlingen, Germany, that manufactures medical devices. Prengel Timo and Wawrzynek Ramona are the current co-CEOs of the firm.

Medical Designs, Inc., part of Sparta Surgical Corp., is a company headquartered in Westerville, OH, involved in electromedical and electrotherapeutic apparatus. On December 30, 1992 Sparta Surgical Corp. acquired Medical Designs, Inc. for $1.26 million.

dj Orthopedics, Inc. provides rehabilitation and regeneration products for the non-operative orthopedic & spine markets. Its Arch Rival is a pre-fabricated orthotic designed to treat subtle cavus foot by promoting natural foot function, improving stability, adding shock absorption, and alleviating pain. The company was founded in 2001 and is located in Vista, CA.

NeuroControl Corp. develops and markets implantable stimulation systems. The company offers electrical stimulator, cranial repair resin kits, surgical hand protectors, helmet lenses, and felts. The company was founded by P. Hunter Peckham in 1993 and is headquartered in Valley View, OH.

Nestec SA, a subsidiary of Nestlé SA, is a Swiss company located in Vevey. The firm manufactures nutrition food products.

Zimmer, Inc. provides joint replacement solutions. The firm products include trauma and dental implants and orthopaedic surgical products. The company was founded in 1927 and is headquartered in Warsaw, IN.

Bay Innovation Group LLC provides medical device incubator which enables inventors to rapidly realize market potential and value from inventions in the medical device area. The company is founded by Jerome B. Riebman and is headquartered in Jamaica Plain, MA.

DJO LLC manufactures orthopedic products. Its products include aircast, CMF, DonJoy, ProCare, Bell-Horn, Compex, Exos, Saunders, VitalStim, And Fast Freeze. The company was founded in 1999 and is headquartered in Vista, CA.

Integra LifeSciences Corp., part of Integra LifeSciences Holdings Corp., is a company headquartered in Princeton, NJ, that manufactures medical devices.

Jiangsu Provincial People's Hospital, a subsidiary of Nanjing Medical University, is a company headquartered in Guangzhou, China. The firm operates hospitals.

National Rehabilitation Center is a Korean public health agency that oversees treatment, rehabilitation research, education and training.

SPRA Therapeutics is a medical device company that is commercializing pain treatments utilizing its proprietary peripheral nerve stimulation (PNS) products. They are developing a pipeline of neurostimulation pain therapies that will exploit the same physiologic mechanism of action, proprietary technology, and clinical approach. The first product to be commercialized is the SMARTPATCHâ„¢ PNS System, which is a short-term, minimally invasive system that is simple to deliver and can be used for up to 30 days to stimulate electrically a peripheral nerve to relieve pain.

Cayenne Medical, Inc. a sports medicine company, provides arthroscopic surgery products. It offers AperFix System that enables the surgeons to perform anterior cruciate ligament (ACL) reconstruction using the hamstring and various soft tissue grafts. The company also provides AperFix Femoral device to restore native knee kinematics; AperFix Tibial device for anatomic reconstruction applications; and iFix Interference Screw System for ACL reconstruction procedure using the bone-patellar tendon-bone and various bone-tendon-bone grafts. In addition, it offers interference screws and shoulder products. Cayenne Medical, Inc. was founded in 2005 and is based in Scottsdale, Arizona.

Ralston Purina Company was a St. Louis, Missouri-based American animal feed and pet food company.