Smith & Nephew PLC designs, manufactures and markets orthopedic devices, sports medicine and ENT technologies, and wound-care solutions. Slightly more than 40% of the U.K.-based firm's revenue comes from orthopedic products, and another 30% is a sports medicine and ENT. The remaining 27% of revenue is from the advanced wound therapy segment. Roughly half of Smith & Nephew's total revenue comes from the United States, just over 30% is from other developed markets, and emerging markets account for the remainder.

Extremity Medical LLC is a private company headquartered in Parsippany, NJ, that manufactures medical instruments. The firm was founded in 2008. Matthew Lyons is the current CEO of the company.\nThe company says this about itself: Extremity Medical, LLC, founded in 2008, is a privately-held medical device company based in Parsippany, NJ, known for creating innovative implants and instruments for upper and lower extremity orthopedic procedures, including fusion and motion preservation. The company is focused on developing solutions for challenging cases that promote better outcomes, especially in patients with poor bone quality.

Synthesis BV engages in the design and production of synthetic water level regulation products. It offers penstocks, pipeline valves, accessories, channel slide gates, fish migration, float units, overflow pits, pivoted weirs, pipes, dirt grates, butterfly valve, and check valves. The company is headquartered in Emmeloord, the Netherlands.

Tianjin Zhengtian Medical Equipment Co., Ltd., established on 2003-01-09, Business scope includes licensed projects:Production of Class II Medical Devices;Production of Class III Medical Devices;Class III medical device business;Production of medical masks.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments,The specific business items are subject to the approval documents or licenses of relevant departments)General project:Import and export;Production of Class I Medical Devices;Sales of Class I Medical Devices;Sales of Class II Medical Devices;Medical Mask Retail;Wholesale medical masks;daily mask(non-medical)Sales;daily mask(non-medical)Production;Medical Research and Experimental Development;Manufacturing of hardware products;Manufacturing of forgings and powder metallurgy products;Sales of forgings and powder metallurgy products;Technical Services,technology development,technical consulting,Technology Exchange,technology transfer,Technology Promotion;Metal Material Sales;Synthetic Materials Sales.(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license)

Manufactures fixation products for the orthopedic community

Beijing Natong Medical Technology Holdings Co., Ltd., established on 2011-05-18, Business scope includes corporate headquarters management;Medical Research and Experimental Development;technology development,Technical Services,technical consulting,technology transfer;Import and export,Agent import and export,Technology Import and Export;production of medical devicesIkind;Sales of medical devicesI,IIkind;Production of the second class,Class III medical devices;Sales of Class III Medical Devices.(Market entities independently choose business projects in accordance with the law,Carry out business activities;Items subject to approval by law,Carry out business activities in accordance with the approved content after approval by relevant departments;Do not engage in the business activities of projects prohibited and restricted by the industrial policies of the state and this city.)

Synthes USA LP used to manufacture medical devices. The company was founded by Hansjörg Wyss in 1974 and is headquartered in West Chester, PA.

Changzhou Aosmai Medical Equipment Co., Ltd., established on 2002-12-04, Business scope includes medical device production[Three categories6846Implantable materials and artificial organs,Class I medical device,Class II6810Orthopedic surgery(orthopedics)Surgical Instruments];medical instruments(limit<Medical Device Business License>Approved scope)Sales;Manufacturing of light sources for medical devices.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments)

Smith & Nephew Richards is a private company headquartered in Memphis, TN, involved in orthopedic, prosthetic, and surgical appliances and supplies.

Part of Zimmer Biomet Holdings, Inc., Zimmer GmbH is a company headquartered in Winterthur, Switzerland, that develops and manufactures non contact instruments for quality monitoring. The firm was acquired by TSI, Inc. (Minnesota) on October 30, 1996.

Jeil Medical Corp. is a private company headquartered in the South Korea. The firm manufactures dental equipment.

Part of Tiger Kanri KK, Prosper Corp. is a company headquartered in Soka, Japan, that provides parcel delivery and related trucking services. Tiger Kanri KK acquired Prosper Corp. on May 12, 2006 for $1.36 million.

Kanghui was founded in 1997 and is headquartered in Changzhou. Kanghui announced today that it requested that trading of its American depositary shares on the NYSE be suspended. Kanghui has requested that the NYSE file Form 25 with the U.S. Securities and Exchange Commission (the “SEC”) notifying the SEC of the delisting of Kanghui’s American depositary shares from NYSE and the deregistration of the Company’s registered securities. Kanghui intends to terminate its reporting obligations under the Securities Exchange Act of 1934, as amended by promptly filing Form 15 with the SEC.

Orthopedic Designs develops, manufactures and markets improved fixation products for the orthopedic community. In keeping with this charter Orthopedic Designs, Inc. offers the finest new developments in orthopedic surgery encompassing its patented process: Talon™ Technology.

Founded in 1986 in China, Trauson, which manufactures spine devices and products for trauma surgeries, accounted for sales of about $60m in 2011. With the introduction of sophisticated manufacturing and processing equipment and measuring instruments, Trauson has also obtained the ISO13485-2003 certification of the China Quality Certification Center for Medical Devices. By the end of 2010, Trauson had received 100 registration certificates for its products. In addition, Trauson's main product has attained CE marks and US FDA 510(K), in 2007 and 2008 respectively. TRAUSON is the only trademark that has been awarded the well-known Chinese Brand in China's orthopedic industry.

Changzhou Kanghui Medical Innovation Co., Ltd. is one of China's leading orthopedic companies, with products in the segments of Trauma, Spine, and Joint Implants & Instruments. With a history of high quality manufacturing and strong domestic sales and marketing capabilities, Kanghui has attracted strong institutional investor support from top tier venture capital companies, including IDG VC Partners, TDF, SIG, CDH and Vivo Ventures.\nKangHui is differentiated from its domestic competitors by its international orientation on product quality and innovation. They spend significantly on R & D to improve their products with a focus on maintaining market leadership in their product segments. Likewise, their quality control team (trained in manufacturing techniques and processes at Komatsu) has helped the company reach international standards in quality. Their collaborations with multi-national orthopedic companies, including Depuy (J&J), Smith & Nephew, Biomet, Stryker and Paragon, are a testament to the quality standards they set for the company.

Part of Zimmer Biomet Holdings, Inc., Biomet CV is a Dutch company. The firm manufactures medical instrument and aids.

TDM Corp. is a private company headquartered in Fletcher, NC. The firm manufactures machine tools.