DePuy Products, Inc., part of Johnson & Johnson, is a company headquartered in the United States. The firm manufactures and distributes orthopaedic devices.

Orthofix SRL manufactures and markets medical devices. The company was founded byGiovanni de Bastiani in 1980 and is headquartered in Bussolengo, Italy.

DePuy Synthes Products, Inc. develops and markets medical products. It offers distal volar Radius, which is designed to treat distal radius fractures, dorsal endoplate, an invasive dorsal nail plate that provides fixed angle support and intramedullary locked fixation with a duplicate and reproducible surgical procedure, spatial subchondral support plate, which is used to treat proximal humeral fractures and Small Bone Fixation System, a percutaneous locked intramedullary nail system for metacarpals and the phalanges. The company was founded on June 22, 2004 and is headquartered in Wilmington, DE.

DePuy Ireland Unlimited Co., part of Johnson & Johnson, is a company headquartered in County Cork, Ireland. The firm develops and markets diagnostic and therapeutic products.

Waldemar Link GmbH & Co. KG is a private company headquartered in Hamburg, Germany, with subsidiaries in the United States and Sweden, that supplies orthopedic products. The firm was founded in 1948. Helmut D. Link, Norbert Ostwald and Peter Heinz Willenborg are the current co-CEOs of the company.

Synthesis BV engages in the design and production of synthetic water level regulation products. It offers penstocks, pipeline valves, accessories, channel slide gates, fish migration, float units, overflow pits, pivoted weirs, pipes, dirt grates, butterfly valve, and check valves. The company is headquartered in Emmeloord, the Netherlands.

Part of Zimmer Biomet Holdings, Inc., Biomet CV is a Dutch company. The firm manufactures medical instrument and aids.

Smith & Nephew PLC designs, manufactures and markets orthopedic devices, sports medicine and ENT technologies, and wound-care solutions. Slightly more than 40% of the U.K.-based firm's revenue comes from orthopedic products, and another 30% is a sports medicine and ENT. The remaining 27% of revenue is from the advanced wound therapy segment. Roughly half of Smith & Nephew's total revenue comes from the United States, just over 30% is from other developed markets, and emerging markets account for the remainder.

DePuy Orthopaedics, Inc. engages in the design, manufacture, and distribution of orthopedic devices and supplies. Its products are used primarily by orthopedic medical specialists and spinal neurosurgeons in both surgical and non-surgical therapy. The company was founded on December 13, 2016 and is headquartered in Warsaw, IN.

Part of Medtronic Plc, Warsaw Orthopedic, Inc. is a company headquartered in the United States that operates orthopedic center.

Wright Medical Technology, Inc., a subsidiary of Stryker Corp., is a company headquartered in Arlington, TN. The firm manufactures orthopedic, prosthetic, and surgical appliances and supplies.

Globus Medical, Inc. operates as a medical device company that develops and commercializes healthcare solutions. The firm engages in developing products that promote healing in patients with musculoskeletal disorders. It classifies products into Innovative Fusion and Disruptive Technology. It operates through the United States and International geographical segments. The company was founded by David C. Paul, David D. Davidar and Andrew Iott in March 2003 and is headquartered in Audubon, PA.

Osteotech, Inc. develops biologic products for orthopedic, spinal, trauma, neurosurgical, and maxillofacial surgeons for use in surgical procedures. It operates in five segments: demineralized bone matrix, hybrid/synthetic, traditional tissue, spinal allograft, and client services. The company processes, markets, and distributes Xenograft bone tissue products, which are used as bone graft substitutes. The company was founded in 1986 and is headquartered in Eatontown, NJ.

Tornier SAS engages in the orthopedic industry. The company was founded on April 27, 1970 and is headquartered in Montbonnot-Saint-Martin, France.

Stanmore Implants Worldwide is an innovative orthopaedic business focused on the design and manufacture of both bespoke and modular implants for limb-sparing and complex primary and revision joint replacement. Stanmore Implants Worldwide designs, manufactures and markets a custom implant service alongside a portfolio of orthopaedic implants for limb salvage and complex joint replacement, and is known for creating some of the world's most successful implants. Stanmore Implants Worldwide acquired its robotic bone preparation technology through the acquisition of Acrobot, a medical devices company specializing in computer-assisted orthopaedic surgery in August 2010. Stanmore Implants Worldwide was acquired by Stryker on April 29, 2016. It was founded in 1948 and is headquartered in London, UK.

BioMarin develops and commercializes innovative biopharmaceuticals for serious diseases and medical conditions. The company's product portfolio comprises three approved products and multiple clinical and pre-clinical product candidates. Approved products include Naglazyme® (galsulfase) for mucopolysaccharidosis VI (MPS VI), a product wholly developed and commercialized by BioMarin; Aldurazyme® (laronidase) for mucopolysaccharidosis I (MPS I), a product which BioMarin developed through a 50/50 joint venture with Genzyme Corporation; and Kuvan® (sapropterin dihydrochloride) Tablets, for phenylketonuria (PKU), developed in partnership with Merck Serono, a division of Merck KGaA of Darmstadt, Germany.

GreenBone develops a wood-derived bone implants technology to generate biomimetic – reabsorbable– load bearing implant suitable to address non-union fractures. The idea was conceived and developed by a research group of ISTEC-CNR of Faenza comprised of Andrea Ruffini, Simone Sprio and Anna Tampieri.

Zimmer, Inc. provides joint replacement solutions. The firm products include trauma and dental implants and orthopaedic surgical products. The company was founded in 1927 and is headquartered in Warsaw, IN.

Part of Medtronic Plc, SDGI Holdings, Inc. is an American company that manufactures medical equipment.