Edwards Lifesciences Corp. engages in patient-focused medical innovations for heart disease and critical care monitoring. Its products are categorized into four main areas: Transcatheter Aortic Valve Replacement, Transcatheter Mitral and Tricuspid Therapies, Surgical Structural Heart, and Critical Care. It operates through the following geographical segments: United States, Europe, Japan, and Rest of World. The company was founded by Miles Lowell Edwards in 1958 and is headquartered in Irvine, CA.

Twelve, Inc. is a holding company, which engages in the operation as an investment fund for a medical device incubator. It specializes on funding and developing medical device inventions. The company focuses on medical and biotech ventures. The company was founded in 2009 and is headquartered in Redwood City, CA.

Harpoon Medical is a development stage medical device company commercializing a minimally invasive, image-guided surgical tool for beating heart mitral valve repair. The technology was developed in the Division of Cardiac Surgery at The University of Maryland School of Medicine. With the Harpoon device, surgeons can access and repair the mitral valve in a beating heart via a small incision between the ribs without the need for cardiac arrest or cardiopulmonary bypass. The tool enters the left ventricle transapically and inserts “bulky knot” neochords in the leaflet to eliminate mitral valve regurgitation. When introduced to the market, the Harpoon device should transform the traditional open-heart mitral valve surgical procedure from a complex 3-6 hour operation to a 60-minute procedure and reduce the recovery period from weeks to days.

Heart Repair Technologies is a leader in the development of innovative products for cardiovascular medicine.

Medtronic, Inc. operates as a medical technology company. It offers implantable cardiac pacemakers, eternal defibrillators, inferior turbinate surgery products, and continuous glucose monitoring device. The company was founded by Earl E. Bakken and Palmer J. Hermundslie on April 29, 1949 and is headquartered in Minneapolis, MN.

Cardiac Dimensions, Inc. develops novel interventional tools for the treatment of heart failure and the related condition of mitral valve regurgitation. It offers the CARILLON Mitral Contour System, a proprietary and implantable device designed to be positioned in the coronary sinus vein using cardiac catheterization techniques. The firm also offers patient enrollment, clinical testing, and medical consulting services. The company was founded by James W. Fitzsimmons and Scott Jordan Wolf in 2001 and is headquartered in Kirkland, WA.

Shanghai NewMed Medical Co., Ltd. engages in research, development, production of artificial heart valves and transcather implantation system. The company was founded by Yu QifengY in March 2015 and is headquartered in Shanghai, China.

Shanghai Shenqi Medical Technology Co., Ltd. is a company headquartered in Shanghai, China, that engages in research, development, production and sale of cardiovascular intervention, peripheral vascular intervention, neurovascular intervention and structural heart disease products. The firm was founded in 2014.

Terumo Cardiovascular provides perfusion products, endoscopic vessel harvesting products, and surgical stabilization products. They provide medical devices and services for the benefit of patients and medical settings in more than 160 countries.

BMEYE B.V., a non-invasive cardiovascular monitoring company, engages in the research and development of medical technologies for cardiovascular monitoring in the Netherlands and internationally. It offers finger arterial pressure and cardiac output technologies. The company's products include Finapres, a non-invasive continuous finger blood pressure monitor; Portapres, an ambulatory non-invasive continuous finger blood pressure monitor for measurements; Finometer, a stationary monitor with options for non-invasive brachial pressure and beat-to-beat hemodynamics; and BeatScope, a software package for the analysis of arterial pressure waveforms. Its products also comprise Modelflow, a model-based measurement method to compute the aortic flow waveform and cardiac outout from an arterial blood pressure waveform; Space instrumentation, a version of finger blood pressure monitors; Cardiopres, an ambulatory device for research on the interaction of electrophysiology, hemodynamics, and respiration; and Oxyflow, a hemodynamics and oxygen delivery monitor for experimental applications. In addition, the company offers Nexfin, a non invasive blood pressure and cardiac output monitor, as well as ccNexfin for applications in various areas, such as cardiology, anesthesiology, sleep observation, physiology, neurology, and internal medicine; and emergency, acute, intensive, and intermediate care. It offers its products through a network of distributors. BMEYE B.V. was founded in 2005 and is based in Amsterdam, the Netherlands.

InnerCore Medical provides surgical repair of the mitral valve to facilitate the procedure, increase its accessibility, and reduce related risks. It began operation on January 1, 2016, with its headquarters in Tel Aviv in Israel.

KOKA Lifesciences Co., Ltd. is a company headquartered in Shanghai, China, that manufactures and sells medical devices. The firm was founded in 2018. Ming Ming Wu is currently the CEO of the company.

Viacor is a development stage company dedicated to pioneering catheter-based techniques for the treatment of heart valve disease contributing to congestive heart failure.\nCurrently, they are focused on the development of a minimally invasive cardiac valve repair system to treat congestive heart failure (CHF) patients afflicted with mitral regurgitation (MR), or 'leaky' mitral valves - a common problem among patients with CHF. Over 750,000 patients in the United States alone have associated functional MR and their mortality rate is double that of patients without MR.\nTheir goal is to provide a new therapeutic alternative that significantly expands the potential to treat this large heart failure population without the risks associated with current surgical procedures. Viacor's Percutaneous Transvenous Mitral Annuloplasty (PTMA®) device has the potential to offer effective treatment with minimal intervention.

Shanghai Lixiao Medical Technology Co., Ltd., established on 2019-01-11, Business scope includes licensed projects:Production of Class II Medical Devices;Production of Class III Medical Devices;Class III medical device business;Import and export;Technology Import and Export.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments,The specific business items are subject to the approval documents or licenses of relevant departments) General project:working in medical technology,Biological Technology(human stem cells,Except for the development and application of genetic diagnosis and treatment technology)technology development in the field,technology transfer,technical consulting,Technical Services;Instrumentation,laboratory equipment,Chemical raw materials and products(Removal of hazardous chemicals,Monitor Chemicals,firecrackers,civilian explosives,precursor chemicals),Equipment,Sales of Electronics;commission agent(except auction);Production of Class I Medical Devices;Sales of Class I Medical Devices;Sales of Class II Medical Devices.(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license)

Part of Abbott Laboratories, St. Jude Medical, Cardiology Division, Inc. is a company headquartered in St. Paul, MN. The firm develops and commercializes minimally invasive cardiovascular and neurovascular medical devices. It was founded by Paul R. Buckman. Lisa D. Earnhardt is currently the CEO of the company.

Onset Medical Corp. founded in 2003, is a privately held medical device technology company located in Irvine, California. Onset is committed to developing and commercializing innovative catheter based medical devices with its proprietary Controlled Deployment Technology platform. Onset Medical an ISO 13485:03 approved manufacturing facility and currently offer a variety of products that are FDA cleared and CE-Mark Approved for commercialization. Its innovative R&D pipeline of products will continue to expand, enhance and enable current and future surgical and interventional therapies.

LSI Solutions, Inc. is an American private company. The firm manufactures and markets invasive surgical instruments.

Boston Scientific Scimed, Inc. develops, manufactures, and markets medical devices used principally to treat cardiovascular disease.