Icagen, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of novel orally-administered small molecule drugs that modulate ion channel targets. It develops ICA-105665 that is in Phase I single dose escalation study in healthy volunteers for epilepsy and neuropathic pain; and Senicapoc, which is in Phase I multiple dose study in healthy volunteers for the treatment of asthma. The company also conducts ongoing drug discovery programs on new therapeutics for pain and inflammatory disorders. Icagen has collaboration agreements with Bristol-Myers Squibb Company; Astellas Pharma, Inc.; and Pfizer, Inc.

At NPS Pharma, the most important thing they make is a difference in the lives of patients with rare diseases. People living with rare diseases have incredible courage. They have to, because they have few, if any, treatment options and are often overlooked because of the rarity of their disorders. Globally, there are approximately 7,000 rare disease and treatments exist for less than 500 of them. They can do better than this. They must do better than this. Their sole focus at NPS Pharma is rare diseases, and they are building a global pipeline of first-in- or best-in-disease therapies. Patients are at the center of everything they do. Each of us brings a personal passion to fulfilling their mission: To pioneer and deliver innovative therapies that transform the lives of patients with rare diseases worldwide. Their values and culture are the most important drivers of their success and will support us in achieving their vision of creating a world where every person living with a rare disease has a therapy. Integrity, respect, excellence, personal ownership, teamwork, entrepreneurial spirit and fun are the values that guide their work each day and what they expect from each other. They are the fabric of the NPS Pharma culture. They develop therapies for patients with significant unmet medical needs. In 2013, they launched their first product in the U.S. called Gattex® (teduglutide [rDNA origin]) for injection, which was also approved in Europe where they are launching it this year in select countries under the trade name Revestive®. NPS Pharma is currently conducting a global registration study for teduglutide in pediatric patients, because children have considerable, unique needs. NPS Pharma is also developing rhPTH [1-84], an investigational medicine being studied for the treatment for Hypoparathyroidism, a rare endocrine disorder characterized by insufficient levels of parathyroid hormone. Hypoparathyroidism is the only classic endocrine disorder without a parathyroid hormone replacement therapy. Their Biologics License Application is currently under FDA review and they are planning to file a European Marketing Authorization Application for rhPTH[1-84] this year. Their lead pipeline candidate is NPSP795, a small molecule being developed for the treatment of Autosomal Dominant Hypocalcemia or ADH. There is no approved therapy for this ultra-rare, life-long genetic disorder that affects both adults and children. They have a Phase 2a proof-of-concept study underway to evaluate NPSP795 for the treatment of adults with ADH. Today, NPS Pharma is a global rare disease company with approximately 300 employees and operations in the U.S., Canada, Europe, Latin America and Japan. They are passionate about transforming the lives of patients with rare diseases through science. Every day, they connect with people living with rare diseases. Every day, they connect with physicians, researchers, universities, policy makers and companies throughout the globe working in rare diseases. Together they can make a difference.

Knoll AG, part of BASF SE, is a company headquartered in Haren, Germany, that develops pharmaceuticals.

F. Hoffmann-La Roche Ltd. manufactures pharmaceutical products. It offers pharmaceutical drugs, pharmaceutical instruments, and diagnostics solutions. The company was founded by Fritz Hoffmann-La Roche on October 1, 1896 and is headquartered in Basel, Switzerland.

XenoPort, Inc. is a biopharmaceutical company focused on developing and commercializing a portfolio of internally discovered product candidates for the potential treatment of neurological disorders. Horizant® (gabapentin enacarbil) Extended-Release Tablets is approved and being marketed in the United States by XenoPort. Regnite® (gabapentin enacarbil) Extended-Release Tablets is approved and being marketed in Japan by Astellas Pharma Inc. XenoPort holds all other world-wide rights to gabapentin enacarbil. XenoPort's pipeline of product candidates includes potential treatments for patients with Parkinson's disease, relapsing-remitting multiple sclerosis and psoriasis.

Part of Addex Therapeutics Ltd., Addex Pharma SA is a company headquartered in Switzerland that discovers and develops allosteric modulators for human health.

Arena Pharmaceuticals, Inc. is a biopharmaceutical company founded in 1997 and located in San Diego, California. The company has small molecule drugs in development for possible clinical utility in multiple therapeutic areas. The company’s most advanced investigational clinical programs are ralinepag (formerly APD811) in testing for pulmonary arterial hypertension (PAH), etrasimod (formerly APD334) in evaluation for inflammatory indications and APD371 for the treatment of pain associated with Crohn’s disease. In 2016 the company downsized and shifted its focus to developing new drugs currently being tested in clinical trials.

Medtronic, Inc. operates as a medical technology company. It offers implantable cardiac pacemakers, eternal defibrillators, inferior turbinate surgery products, and continuous glucose monitoring device. The company was founded by Earl E. Bakken and Palmer J. Hermundslie on April 29, 1949 and is headquartered in Minneapolis, MN.

Smithkline Beecham Plc develops and manufactures pharmaceutical products. The company markets pharmaceuticals for human and animal healthcare consumption, vaccines, over the counter medicines, health related consumer products, clinical laboratory testing services, disease management and pharmaceutical benefit management. It is headquartered in Brentford, UK.

Allergan, Inc. operated as a global healthcare company. It engaged in the development and commercialization of specialty pharmaceutical, medical device ,and over-the-counter products for the ophthalmic, neurological, medical aesthetics, medical dermatology, breast aesthetics, obesity intervention, urological, and other specialty markets. The company was founded by Gavin S. Herbert in 1950 and headquartered in Irvine, CA.

N.V. Organon engages in the development, manufacture, and sale of prescription medicines. It offers products for cardiovascular diseases, fertility, gynecology, anesthesia, respiratory, consumer health care, neuroscience as well as immunology, animal health, and oncology. Its products include mometasone furoate inhalation powder, moxifloxacin, pegylated liposomal doxorubicin HCI, desogestrel, desloratadine, sun care, flu medicine, foot care, follitropin beta, formoterol fumarate inhalation powder, hormone therapy, and canine vaccines. The company was founded in 1923 and is headquartered in Oss, the Netherlands.

Merz Pharma GmbH & Co. KGaA is an innovative and international healthcare company with its own research and development department. It focuses on drugs for the treatment of illness in the fields of neurology and psychiatry. The company is bundling the activities of its subsidiaries Merz Pharmaceuticals, Merz Consumer Care, Merz Dental, and Merz Hygiene, with products ranging from prescription drugs and OTC products for health and wellness, materials for dentists and dental technicians to hygienic products for medical disinfection and cleaning.\nThe units of Merz Group Services, the fith Merz subsidiary, include Human Resources, Supply Chain/Purchasing, Information Technology (IT), Technical Operations and Finances/Controlling.

Merck Sharp & Dohme BV, a subsidiary of Merck & Co., Inc., is a Dutch company located in Oss. The firm manufactures and distributes pharmaceutical products.

Teva Pharmaceutical Industries Ltd. engages in the development, production, and sale of medicines. It operates through the following geographical segments: North America, Europe, and International Markets. The company was founded in 1901 and is headquartered in Tel Aviv, Israel.

Institut National de la Sant? et de la Recherche M?dicale provides medical services. The firm specializes in biomedical research and public health research. The company is headquartered in Paris, Cedex, France.

Knorr-Bremse GmbH manufactures braking systems and sub-systems for rail and commercial vehicles. It offers magnetic track and eddy current breaks, flange devices, windscreen wiper and washing systems, sanding systems, and brake test units. The company was founded by Georg Knorr in 1905 and is headquartered in Mödling, Austria.

Sun Pharmaceutical Industries Ltd. engages in manufacturing, developing, and marketing of pharmaceuticals products. It offers tablets, capsules, injectable, inhalers, ointments, creams, and liquids. The company was founded by Dilip Shantilal Shanghvi in 1983 and is headquartered in Mumbai, India.

Laboratorios Senosiain SA de CV engages in the development and manufacture of pharmacetical products. These include antibiotics, suppositories, and analgesics. The company is based in Mexico City, Mexico.

Akzo Nobel NV is a holding company, which engages in the manufacture and sale of coating and paint products. engages in the production and marketing of paints and coatings. It operates through the following segments: Decorative Paintings, Performance Paintings, and Corporate and Others. The Decorative Paints segment manufactures and supplies a range of interior and exterior decoration and protection products for professional and do-it-yourself markets. The Performance Coatings segment produces automotive and aerospace; industrial; marine and protective; and powder coatings. The company was founded in 1792 and is headquartered in Amsterdam, Netherlands.