49results about Nalbuphine companies
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Nalbuphine, sold under the brand names Nubain among others, is an opioid analgesic which is used in the treatment of pain. It is given by injection into a vein, muscle, or fat. Side effects of nalbuphine include sedation, sweatiness, clamminess, nausea, vomiting, dizziness, vertigo, dry mouth, and headache. Unlike other opioids, it has little to no capacity for euphoria or respiratory depression. It also has little to no incidence of dysphoria, dissociation, hallucinations, and related side effects at typical therapeutic doses. Nalbuphine is a mixed agonist/antagonist opioid modulator. Specifically, it acts as a moderate-efficacy partial agonist agonist or antagonist of the μ-opioid receptor (MOR) and as a high-efficacy partial agonist of the κ-opioid receptor (KOR), whereas it has relatively low affinity for the δ-opioid receptor (DOR) and sigma receptors.
Trevi Therapeutics, Inc.
2011
|
United States
|
10-50
|
http://www.trevitherapeutics.com
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Public Company
Trevi Therapeutics is a clinical-stage biopharmaceutical company focused on the development and commercialization of nalbuphine ER to treat serious neurologically mediated conditions. Trevi is currently developing nalbuphine ER for the treatment of chronic pruritus, chronic cough in patients with idiopathic pulmonary fibrosis (IPF), and levodopa-induced dyskinesia (LID) in patients with Parkinson’s disease. These conditions share common pathophysiology that is mediated through opioid receptors in the central and peripheral nervous systems. Trevi is currently conducting a Phase 2b/3 clinical trial of nalbuphine ER, referred to as the PRISM trial, in patients with severe pruritus associated with prurigo nodularis.
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Clinical trial
Nalbuphine
Counterirritant
Patiromer
Chronic pruritus
Uremic pruritus
Prurigo nodularis
Levodopa-induced dyskinesia
Opioid receptor
Dyskinesia
Peripheral nervous system
Pathophysiology
Idiopathic pulmonary fibrosis
Biopharmaceutical
Drug
...[+12]
Debregeas Et Associes Pharma
2006
|
France
|
10-50
|
http://www.da-pharma.com
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Private Company
D&A Pharma develops and manufactures pharmaceutical products.
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Lumosa Therapeutics Co., Ltd.
2001
|
China
|
100-250
|
http://www.lumosa.com.tw
|
Public Company
Lumosa Therapeutics, a public traded company in Taipei Exchange (6535.TWO), is dedicated to the development of innovative new drugs for the treatment of neurological and inflammatory diseases of unmet medical needs. The company is actively engaged in scientific in-licensing and new drug development under the “reSEARCH and DEVELOPMENT” model. This model is executed by a highly capable and experienced cross-functional teams of translational research, CMC, preclinical, clinical development, project management, regulatory affairs, intellectual property and business development experts.
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Drug development
Translational research
Medicine
Regulatory affairs
Celecoxib
Intellectual property
Drug
Opioid
Project management
Analgesic
Diclofenac/Misoprostol
Zolmitriptan
Tapentadol
Sumatriptan
Capsaicin
Ibuprofen
Morphine
Oxycodone
Sufentanil
Naproxen
...[+17]
Shanghai Lumosa Therapeutics Co., Ltd.
2015
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China
|
-
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-
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Private Company
Shanghai Shengshun Biotechnology Co., Ltd., established on 2015-03-17, The scope of business includes engaging in biotechnology(Development and application of human stem cell gene diagnosis and treatment technology),Medical Technology(Development and application of human stem cell gene diagnosis and treatment technology)technology development in the field,technical consulting,Technical Services,technology transfer,Business Consulting,Business Management Consulting,Wholesale of daily necessities,import and export,commission agent(except auction)and related services.
[Items subject to approval by law,Business activities can only be carried out after approval by relevant departments]
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Endo Pharmaceuticals, Inc.
1920
|
United States
|
-
|
http://www.endo.com/endopharma
|
Subsidiary Company
Endo Pharmaceuticals, Inc. manufactures and distributes pharmaceutical products. The company provides research and development of generic pharmaceutical products for controlling pain. Its product includes Lidoderm, Percocet, Percodan, Frova, DepoDur, and Zydone. The company is headquartered in Malvern, PA.
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Controlling pain
Medicine
Opioid
Analgesic
Neuropathic pain
Female infertility
Ovulation
Male infertility
Infertility
Methadone
Morphine
Oxycodone
Fertility
Codeine
Cannabis
Prostate-specific antigen
Hydrocodone
Pethidine
Reproductive health
...[+16]
EIDP, Inc.
1802
|
United States
|
10,000-50,000
|
https://www.corteva.com
|
DuPont offers sustainable solutions for agriculture, electronics, communications, construction, transportation, and apparel markets. Their products and services include construction materials, fabrics, packaging materials, medical devices, electronic solutions, and adhesives for markets. They provide specialized construction materials to create and maintain roads, bridges, telecommunications, power, and water plants.
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Agriculture
Materials science
Electronics
Pesticide
Nutrition
Synthetic rubber
Science and engineering
Medicine
Enzyme
Soy protein
Pea protein
Engineering plastic
Gluten
Textured vegetable protein
Vitamin
Rice protein
Thermoplastic
Polymer
Preservative
...[+16]
Noramco, Inc.
1979
|
United States
|
500-1,000
|
http://www.noramco.com
|
Holding Company
Noramco was formed in 1979 to design, construct and manage a bulk active pharmaceutical ingredient plant in Wilmington, Delaware to support Ortho-McNeil Pharmaceutical's Tylenol® with codeine business. With the acquisition of Tasmanian Alkaloids and addition of the Athens, Georgia site in 1982, and continuous expansions over the past three decades at both US facilities, Noramco now contributes to billion dollar affiliate franchises, as well as to significant 3rd party generic and branded pharmaceutical products worldwide.
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Pharmaceutical manufacturing
Alkaloid
Medicine
Good manufacturing practice
Contract research organization
Exosome
Biomedicine
Biotechnology
Noramco LLC
|
United States
|
-
|
-
|
Private Company
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Mallinckrodt Medical BV
|
Netherlands
|
-
|
http://www.covidien.nl
|
Subsidiary Company
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DuPont Merck Pharmaceutical Co.
|
United States
|
-
|
-
|
Subsidiary Company
Part of Corteva, Inc., DuPont Merck Pharmaceutical Co. is an American company located in Wilmington, DE. The firm makes pharmaceuticals and drugs. E.I. du Pont de Nemours & Co., now a subsidiary of Corteva, Inc. acquired DuPont Merck Pharmaceutical Co. from Merck & Co., Inc. on July 01, 1998 for $2,600 million.
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Medicine
Saneca Pharmaceuticals AS
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Slovakia
|
-
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http://www.saneca.com
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Private Company
Saneca Pharmaceuticals AS is a Slovak (SK*) private company located in Hlohovec. The firm provides pharmaceutical services.
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Medicine
Active ingredient
Pharmaceutical manufacturing
Biobank
Microarray
Cell signaling
Exosome
Biomedicine
Biotechnology
...[+6]
ALZA Corp.
1968
|
United States
|
1,000-5,000
|
-
|
Subsidiary Company
ALZA Corp. is a pharmaceutical and medical systems company that develops, manufactures, and markets therapeutic systems. It provides oral, transdermal, implantable, and liposomal technologies.
It is also focused on drug delivery systems with over 20 prescription pharmaceutical products.
With over 10,000 employees, ALZA Corp. is a subsidiary of Johnson & Johnson. It was established in 1968 by Dr Alejandro Zaffaroni. It is based inVacaville, California.
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Pharmacy and Therapeutics
Medical product
Medical equipment
Medicine
Euro-Celtique SA
|
Luxembourg
|
-
|
-
|
Private Company
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Algos Pharmaceutical Corp.
|
United States
|
-
|
-
|
Subsidiary Company
Algos Pharmaceutical Corp., part of Endo International Plc, is an American company located in Neptune, NJ, that develops and makes pain management products including narcotic drugs. Endo Health Solutions, Inc. acquired Algos Pharmaceutical Corp. on July 17, 2000 for $243.89 million.
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Drug
Medicine
Penwest Pharmaceuticals Co.
1991
|
United States
|
10-50
|
http://www.penwest.com
|
Private Company
Penwest Pharmaceuticals Co. is a speciality pharmaceutical company focused on the development and commercialisation of therapies for the treatment of neurological disorders. Its oral controlled release technologies are also available for the development and commercialisation of products in multiple therapeutic areas. The company was founded in 1991 and is headquartered in Patterson, NY.
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Neurological disorder
Therapeutic Area
Botanical drug
Herb
Dendropharm GmbH
2013
|
Germany
|
-
|
http://www.dendropharm.de
|
Private Company
DendroPharm GmbH offers young companies which develop novel API (small and large molecule drugs), semi-solid formulations or parenteral liquid formulations, accelerator services. We manufacture your finished drug under GMP for stability studies and clinical trial samples. We offer office space for startups. We also provide partial in-kind investments, consulting and business development services.
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Clinical trial
Drug
Regents of the University of California
1868
|
United States
|
-
|
http://www.ucop.edu
|
Subsidiary Company
The University of California is the nation's best public university system, delivering top-notch research and innovation to California (and the world).
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Pathology
Companion diagnostic
BioLinc
1962
|
Canada
|
-
|
http://www.brocku.ca/biolinc
|
Private Company
The Goodman School of Business BioLinc is part of Innovate Niagara’s network of incubators. BioLinc is a dynamic bioscience, biotechnology, applied health and biomanufacturing business incubation facility dedicated to promote, enhance, and commercialize the discoveries that are taking place at Brock, while bringing Niagara’s health, bioscience, and biomanufacturing sectors to the next level.
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Chemistry
Biology
Medicine
Biochemistry
Internal medicine
Endocrinology
Organic chemistry
Computer science
Clinical psychology
Ecology
Cognition
Condensed matter physics
...[+9]
Suzhou Enhua Biomedical Technology Co., Ltd.
2018
|
China
|
-
|
-
|
Private Company
Suzhou Enhua Biomedical Technology Co., Ltd., established on 2018-07-02, Business scope includes chemical drugs,biomedicine,Chinese herbal medicine,medical instruments,Technical development of diagnostic testing products,technical consulting,Technical Services,technology transfer.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments)
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Yichang Humanwell Pharmaceuticals Co., Ltd.
2001
|
China
|
-
|
http://www.ycrenfu.com.cn
|
Subsidiary Company
Yichang Humanwell Pharmaceuticals Co., Ltd., part of Humanwell Healthcare (Group) Co., Ltd., is a Chinese company located in Yichang that develops and manufactures medicines and pharmaceutical products.
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Pharmacy
Medicine
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