Ardian, Inc. manufactures the symplicity catheter systems. It is a medical device company that develops and researches catheter-based treatment for diseases such as hypertension, chronic kidney diseases, metabolic syndrome and heart failure. The company was founded by Denise Demarais Zarins, Allan R. Will, Henry A. Plain Jr., Howard R. Levin and Mark Gelfand in 2003 and is headquartered in Mountain View, CA.