Prenatal testing consists of prenatal screening and prenatal diagnosis, which are aspects of prenatal care that focus on detecting problems with the pregnancy as early as possible. These may be anatomic and physiologic problems with the health of the zygote, embryo, or fetus, either before gestation even starts (as in preimplantation genetic diagnosis) or as early in gestation as practicable. Screening can detect problems such as neural tube defects, chromosome abnormalities, and gene mutations that would lead to genetic disorders and birth defects, such as spina bifida, cleft palate, Downs Syndrome, Tay–Sachs disease, sickle cell anemia, thalassemia, cystic fibrosis, muscular dystrophy, and fragile X syndrome. Some tests are designed to discover problems which primarily affect the health of the mother, such as PAPP-A to detect pre-eclampsia or glucose tolerance tests to diagnose gestational diabetes. Screening can also detect anatomical defects such as hydrocephalus, anencephaly, heart defects, and amniotic band syndrome.
Sequenom, Inc.
https://womenshealth.labcorp.com
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Sequenom (NASDAQ: SQNM) is an American company based in San Diego, California. It develops enabling molecular technologies, and highly sensitive laboratory genetic tests for NIPT. Sequenom's wholly owned subsidiarity, Sequenom Center for Molecular Medicine (SCMM), offers multiple clinical molecular genetics tests to patients, including MaterniT21, plus a noninvasive prenatal test for trisomy 21, trisomy 18, and trisomy 13, and the SensiGene RHD Fetal RHD genotyping test.
Trisomy
Coronavirus
Medical equipment
Molecular diagnostics
Immunoassay
Systems design
Microbiology Test
Cryptosporidium
Microbiology
Retinal Disorder
Toxoplasmosis
Molecular medicine
Molecular genetics
Tumor marker
Malaria
Genomics
Lymphokine
Oncogene
Oncology
Verinata is driven by a sole, extraordinary purpose – maternal and fetal health. Our initial focus is to develop and offer non-invasive tests for early identification of fetal chromosomal abnormalities using our proprietary technologies. We aim to reduce the anxiety associated with today's multi-step process, the unacceptable false-positive rates, the non-specific and sometimes confusing results of current prenatal screening methods, as well as the risk of current invasive procedures. In support of national guidelines recommending first trimester aneuploidy risk assessment, we believe women who desire such an assessment should be offered a single blood draw test with a definitive result. Verinata is conducting a prospective, blinded pivotal study to clinically validate the sensitivity and specificity of its first prenatal test on a large scale with results of the study expected in 2011.
Software development
Medical equipment
Prenatal screening
Invasive Procedure
Anxiety
Risk assessment
Genetic testing
Molecular diagnostics
Genomics
Abortion
Maternal-fetal medicine
Family planning
Prenatal care
Neonatology
Obstetrics
Breast cancer
Gynecology
Fertility
Pathology
Natera, Inc. is a diagnostics company, which engages in the discovery, development, and commercialization of genetic testing services. It provides Panorama non-invasive prenatal test (NIPT), Vistara, horizon carrier screening (HCS), spectrum pre-implantation genetic screening and spectrum pre-implantation genetic diagnosis, Anora products of conception (POC) and non-invasive paternity testing (PAT). The firm also offers Constellation, a cloud-based software product that allows laboratory customers to gain access to the algorithms and bioinformatics in order to validate and launch tests based on the technology. The company was founded by Matthew Rabinowitz and Jonathan Sheena in November 2003 and is headquartered in Austin, TX.
Genetic diagnosis
Genetic testing
Products of conception
Genomics
Bioinformatics
Liquid biopsy
Biopsy
Newborn screening
Genome
Polymerase chain reaction
Exosome
Preimplantation genetic diagnosis
Molecular diagnostics
DNA sequencing
Companion diagnostic
Software
Panitumumab
Pharmacogenomics
Cetuximab
F. Hoffmann-La Roche Ltd.
F. Hoffmann-La Roche Ltd. manufactures pharmaceutical products. It offers pharmaceutical drugs, pharmaceutical instruments, and diagnostics solutions. The company was founded by Fritz Hoffmann-La Roche on October 1, 1896 and is headquartered in Basel, Switzerland.
Medicine
Drug
Clinical trial
Biopharmaceutical
Genomics
Cancer research
Oncology drugs
Diagnostic test
Polymerase chain reaction
Neuroscience
Oncology
Cancer
Clinical chemistry
Genetic testing
Molecular diagnostics
Immunochemistry
Hematology
Tuberculosis
Urinalysis
Illumina is an innovative technology and revolutionary assays aiming the analyze genetic variation and function.
These studies will help make the realization of personalized medicine possible. With such rapid advances in technology taking place, it is mission-critical to have solutions that are not only innovative, but flexible, scalable, and complete with industry-leading support and service. As a company that places a high value on collaborative interactions, rapid delivery of solutions, and prioritizing the needs of its customers, they strive to meet this challenge. Illumina's innovative, array-based solutions for DNA, RNA, and protein analysis serve as tools for disease research, drug development, and the development of molecular tests in the clinic.
David R. Walt, Satnam Alag, Larry Bock, and John Stuelpnagel co-founded Illumina in San Diego, California in 1998.
Molecular diagnostics
Genetic variation
Assay
RNA
Biology
Personalized medicine
DNA sequencing
Microbiology Test
Polymerase chain reaction
DNA
Microbiology
Immunoassay
Coronavirus
Drug development
Genomics
Genome
Bioinformatics
Molecular biology
Computational biology
The General Hospital Corp.
http://www.massgeneral.org
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Massachusetts General Hospital was established to provide care to Boston's sick, regardless of socioeconomic status—an innovative idea in 1811. In the words of their founder, John Warren, MD, “When in distress, every man becomes their neighbor.” They subsequently became the first teaching hospital for Harvard University’s new medical school and have been redefining excellence in healthcare ever since. They have remained at the forefront of medicine by fostering a culture of collaboration, pushing the boundaries of medical research, educating the brightest medical minds and maintaining an unwavering commitment to the diverse community they were created to serve.
They believe that because of diversity they excel, through inclusion they respect their community, and with a keen focus on equity they serve, heal, educate and innovate at the highest levels. Their first priority is the well-being of their patients—near and far. As a team they are able to maintain a singular focus on providing the highest quality, most compassionate care to each and every patient.
Vascular Medicine
Digestive disorder
Subspecialty
Heart disease
Surgery
NIPD Genetics Ltd., a subsidiary of Medicover AB, is a company headquartered in Nicosia, Cyprus, that operates as biotechnology company. The firm was founded in 2010 by Philippos C. Patsalis, who is currently the CEO of the firm. Medicover AB acquired NIPD Genetics Ltd. on January 18, 2022 for $50.32 million.
Biotechnology
DNA sequencing
Precision medicine
Newborn screening
Genome
Single-cell analysis
Prenatal care
Metagenomics
Genetic analysis
Genomics
Exosome
Third generation sequencing
Liquid biopsy
Biopsy
Genetic testing
Molecular diagnostics
Genomic medicine
Molecular medicine
Childbirth
Massive parallel sequencing
ARCEDI is a biotech company, develops technologies and methods for detecting and diagnosing rare cancer cells, as well as methods that will replace placenta biopsies with blood samples.
ARCEDI provide a simpler, safer and accurate non-invasive prenatal diagnostic test to the pregnant women by analyzing the genome of the fetus using circulating fetal cells in maternal blood.
Biopsy
Cancer cell
Cancer
Placenta
Fetus
Maternal-fetal medicine
Family planning
Prenatal care
Neonatology
Obstetrics
Liquid biopsy
Genome
Gynecology
Fertility
Diagnostic test
Pathology
Newborn screening
Cell
Exosome
Institut National de la Santé et de la Recherche Médicale
Institut National de la Sant? et de la Recherche M?dicale provides medical services. The firm specializes in biomedical research and public health research. The company is headquartered in Paris, Cedex, France.
Public health
Genomics
Antisense therapy
Epigenomics
Epigenetics
RNA interference
Messenger RNA
microRNA
Precision medicine
Genomic medicine
RNA
Genome
Cell signaling
Assistance Publique des Hôpitaux de Paris SA
Assistance Publique des Hôpitaux de Paris SA the company is headquartered in Paris, France.
Systemic scleroderma
Podiatrist
Rheumatology
Anatomy
Psoriasis
Primary care
Umbilical Cord Blood Stem Cell
Joint replacement
Dermatology
Induced pluripotent stem cell
Progenitor cell
Cord blood
Blood stem cell
Embryonic stem cell
Stem-cell therapy
Adult stem cell
Safety syringe
Autoinjector
Wayne State University Board of Governors
LifeCodexx AG
http://www.lifecodexx.com
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LifeCodexx AG, part of Eurofins Scientific SE, is a German company located in Konstanz. The firm develops clinically validated molecular diagnostics.
Molecular diagnostics
Medicine
Prenatal care
Companion diagnostic
Abortion
Infertility
Obstetrics
Gynecology
Genetic testing
Newborn screening
Circulating tumor DNA
Genomics
Childbirth
Adenomyosis
Amenorrhea
Vaginitis
Radioimmunoassay
Diagnostic microbiology
Endometriosis
Gynecological cancer
New England Medical Center Hospitals, Inc
Esoterix Genetic Laboratories LLC
Flinders Technology Pty Ltd.
Monaliza Medical Ltd. develops a genetic test platform enabling prenatal genetic screening in Transcervical Cell samples taken in the first trimester of pregnancy. It develops non-invasive prenatal screening and diagnostic tests for early detection of fetal abnormalities. The company was founded in 2004 and is headquartered in Ra'anana, Israel
Test platform
Medicine
Guidance system
Prenatal screening
Diagnostic test
Fetal abnormality
IP2IPO Innovations Ltd.
http://www.imperialinnovations.co.uk/index.php?option=com_content&task=view&id=30&grp=4
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Imperial Innovations is a technology commercialization and venture capital investor that focuses on technology. Imperial Innovations no longer invests in startups and now functions as the technology-transfer office of Imperial College.
Imperial Innovations is focused on commercialising leading UK academic research sourced from the 'golden triangle' formed between Cambridge, Oxford and London. We are a technology commercialisation company that combines the activities of technology transfer, intellectual property protection and licensing, company incubation and investment.
Innovations is focused on commercialising the most promising UK academic research across a broad range of technology sectors, and has developed particular expertise in: therapeutics, medtech, engineering and materials and information communication technology.
Technology transfer
Incubation
Intellectual property
Invites Biocore Co., Ltd.
Invites Biocore is a biotechnology company that conducts experiments on biological organisms for pharmaceutical companies, contract research organizations (CROs), healthcare institutions, and research centers focused on pharmaceutical-related studies.
Founded in 2001, Invites BioCore is a company offering Contract Research Organization (CRO) services specializing in genomic analysis and clinical trials. Their dedication spans the pre-clinical stage of drug development, genetic testing for various life stages, in vitro diagnostic production, and cold chain bio-logistics services.
Clinical trial
Liquid biopsy
Biopsy
Medicine
Drug development
Exosome
Vitatex, Inc. focuses on advance personalized medicine with tests of invasive circulating tumor cells. It develops proprietary diagnostic tests that can be run on blood samples, collected by standard current methods, to improve cancer treatment decisions and select effective therapies for recurrence and metastatic diseases. The company was founded by Wen-Tien Chen and is headquartered in Stony Brook, NY.
Medicine
Medical equipment
Drug
Companion diagnostic
Personalized medicine
Proprietary drug
Diagnostic test
Prescription drug
Cancer
Clinical pathology
Circulating tumor cell
Exosome
Ipilimumab
Preimplantation genetic diagnosis
Biotechnology
Prostate-specific antigen
Cancer marker
Breast cancer
Pap test
Gynecology
The Board of Regents of The University of Texas System
The Board of Regents of The University of Texas System, a subsidiary of The University of Texas at Austin, is an American company located in Austin, TX. The firm oversees college activities.
Oncogene
Cancer immunotherapy
Oncology drugs
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