Alcon, Inc. engages in the development, manufacture, and marketing of market surgical equipment and devices, pharmaceutical eye drops, and consumer vision care products to treat eye diseases and disorders. It operates through the following segments: Surgical and Vision Care. The Surgical segment offers implantable products, consumables and equipment for use in surgical procedures to address cataracts, vitreoretinal conditions, refractive errors, and glaucoma. The Vision Care segment comprises daily disposable, reusable and color-enhancing contact lenses, as well as portfolio of ocular health products, including over-the-counter products for dry eye, contact lens care, and ocular allergies, as well as ocular vitamins and redness relievers. The company was founded by Mr. Robert Alexander and Mr. William Conner on 1945 and is headquartered in Geneva, Switzerland.

WaveLight AG produces laser-systems for optimizing medical procedures. The company's product is LASIK applications, which is used for eye operation. The company was founded by Maximilian Reindl on April 30, 1996 and is headquartered in Erlangen, Germany

Technolas Perfect Vision GmbH is a leading ophthalmology laser company, formed through a joint venture between Bausch + Lomb, and 20/10 PERFECT VISION AG. Technolas Perfect Vision has a full range of expertise in both femtosecond and excimer businesses. Current innovations focus on laser cataract surgery and the correction of presbyopia with the SUPRACOR™ laser treatment.

IntraLase Corporation is a leader in the first step of LASIK surgery, the most common means of surgical vision correction. They design, develop and market a laser, related software and disposable devices used to create a cut of tissue across the cornea of a patient’s eye, or a corneal flap, which is the first step in LASIK surgery. Their advanced laser technology improves the safety, precision and visual acuity of LASIK surgery by providing a computer-controlled laser solution as an alternative to the traditional method of creating the corneal flap using a hand-held mechanical, metal-bladed device called a microkeratome. They believe their product offering will become the new standard of care for corneal flap creation. As of April 2, 2007, IntraLase Corp. was acquired by Advanced Medical Optics Inc.

The Brien Holden Vision Institute (BHVI) is an Australian nonprofit non-governmental organization with an international focus on eye care research and vision care delivery. Formerly the Institute for Eye Research, in 2010 it was renamed in recognition of co-founder Brien Holden, a 1997 recipient of the Medal of the Order of Australia for his contributions to eye care research.

Carl Zeiss Meditec AG engages in the development, manufacture and marketing of medical devices. It operates through the Ophthalmic Devices and Microsurgery business segments. The Ophthalmic Devices segment includes intraocular lenses, surgical visualization solutions and medical laser and diagnostic systems. The Microsurgery segment offers surgical microscopes and visualization solutions for neuro, ear, nose, and throat surgery, as well as the activities in the field of intraoperative radiotherapy. The company was founded on July 2002 and is headquartered in Jena, Germany.

Nidek Co. Ltd. develops ophthalmic surgical and diagnostic equipment for the optical and eye care industries. It offers ophthalmic surgical devices, examination and diagnostic devices, electronic medical record and practice management medical filing systems, intra-ocular lenses and dermatological surgical lasers. The company was founded by Hideo Ozawa in July 1971 and is headquartered in Gamagori, Japan.

LaserSight Technologies, Inc. is a company headquartered in Winter Park, FL. The firm provides vision solutions for the refractive vision correction industry. On December 22, 2009 New Industries Investment Consultants (HK) Ltd. acquired LaserSight Technologies, Inc. from LaserSight, Inc.

Bausch & Lomb is a Canadian eye health products company based in Laval, Quebec, Canada. It is one of the world's largest suppliers of contact lenses, lens care products, pharmaceuticals, intraocular lenses, and other eye surgery products. The company was founded in Rochester, New York in 1853 by optician John Bausch and cabinet maker turned financial backer Henry Lomb. Until its sale in 2013, Bausch & Lomb was one of the oldest continually operating companies in the US.

Sylentis is a biotech company founded in 2006 and wholly owned by Pharma Mar S.A. (PHM:SM), with the mission of building a solid and sustainable business and becoming a leader of a new class of medicines based on RNA interference or RNAi. RNAi is a promising approach to silence targets involved in many diseases and represents a new drug mechanism of action. The Sylentis pipeline is aimed at indications with an elevated market potential, including ocular pathologies, inflammatory diseases and central nervous system diseases. Given the inherent complications of this technology regarding delivery of the active principle to the target tissue, our strategy is based on first selecting accessible therapeutic targets, which don not require systemic administration of the product. However, the development of formulations for RNAi technology to increase the therapeutic effect of these molecules is an area of great interest to the company

Clarity Medical Systems, Inc. developed, manufactured, and marketed integrated optical systems and services. Its products included Holos Intraop, Retcam3, Retcam Shuttle, and RCRS. The company was founded by Wei Su on February 13, 1991 and was headquartered in Pleasanton, CA.

ISTA Pharmaceuticals is a commercial-stage multispecialty pharmaceutical company. It discovers, develops, and markets remedies for diseases and conditions of the eye in the United States. The company offers products to treat allergies and serious diseases of the eye; and therapies for ocular inflammation and pain, glaucoma, dry eye, and ocular and nasal allergies. The company’s marketed products comprise of BROMDAY, a bromfenac ophthalmic solution for the treatment of postoperative inflammation and reduction of ocular pain in patients who have undergone cataract extractions; BEPREVE, a bepotastine besilate ophthalmic solution for ocular itching associated with allergic conjunctivitis; ISTALOL, a timolol maleate ophthalmic solution for the treatment of glaucoma; and VITRASE, a hyaluronidase injection for use as a spreading agent. Its products under development include OTC artificial tear products to treat dry eye and other ocular conditions; PROLENSA, a bromfenac ophthalmic solution for the treatment of postoperative inflammation and reduction of ocular pain after cataract extractions; T-PRED for steroid responsive inflammation; BEPOMAX and BEPOSONE nasal sprays for treating allergic rhinitis; and Bromfenac Adjunct for age-related macular degeneration. In addition, the company develops iganidipine to enhance ocular nerve blood flow; latanoprost, a prostaglandin for the treatment of glaucoma; and ecabet sodium for the treatment of dry eye. ISTA Pharmaceuticals sells its products to drug wholesalers; retailers and distributors such as chain drug stores, hospitals, clinics, and government agencies; and managed healthcare providers including health maintenance organizations and other institutions. ISTA Pharmaceuticals was founded in 1992 and is headquartered in Irvine, California. As of June 5, 2012, ISTA Pharmaceuticals operates as a subsidiary of Bausch & Lomb Incorporated.

ReVision Optics, Inc. designs, manufactures, and delivers implantable products for the treatment of presbyopia. It offers PRESBYLENS Corneal Inlay, a refractive surgery solution to correct vision lost by the natural aging process called presbyopia. The company serves the ophthalmology professionals. ReVision Optics, Inc. was formerly known as IntraLens Vision, Inc. and changed its name to ReVision Optics, Inc. in 2005. The company was founded in 1996 and is based in Lake Forest, California.

Manufactures retrative eye surgery equipment

Nanomerics Ltd. is a British private company. The firm develops precision medicines.\nThe company says this about itself: Nanomerics Ltd is a speciality pharmaceutical company based in London, UK. Nanomerics was spun out of University College London, a top 10 global university and was founded to commercialise its biocompatible polymer technologies for drug delivery and other applications. Nanomerics' proprietary technology is based on world leading know-how and scientific leadership in polymer nanotechnology. Nanomerics creates uniquely differentiated, patented pharmaceutical assets, underpinned by high quality science. For example, the company's Molecular Envelope Technology (MET) is a unique patented biocompatible polymer that delivers a step change in target tissue bioavailability. The founding scientists Professor Ijeoma F. Uchegbu and Professor Andreas G. Schätzlein developed the technology at the Universities of Strathclyde and Glasgow and, latterly at the UCL School of Pharmacy. Pharmaceutical product candidates in development include OC134 for the treatment of allergic conjunctivitis and OC137 for the treatment of non-infectious posterior uveitis.