DePuy Products, Inc., part of Johnson & Johnson, is a company headquartered in the United States. The firm manufactures and distributes orthopaedic devices.

Paradigm Spine, LLC (Paradigm Spine) is a privately-held medical device company, engaged in the development of spinal implants for the spine and orthopedic markets. It develops non fusion spinal implants, motion preserving products and tissue sparing products. Paradigm Spine's product Coflex, an interspinous implant used in the treatment of facet arthosis and decompressive procedures. Its products are used for spinal stabilization, rebalances spinal segment and restores natural anatomical function. The company is headquartered in New York, the US. The company also focused on the development of DSS system, a minimally-invasive pedicle-screw based system, which received a European CE Mark in April 2007 and FDA market clearance in January 2008.

DePuy Synthes Products, Inc. develops and markets medical products. It offers distal volar Radius, which is designed to treat distal radius fractures, dorsal endoplate, an invasive dorsal nail plate that provides fixed angle support and intramedullary locked fixation with a duplicate and reproducible surgical procedure, spatial subchondral support plate, which is used to treat proximal humeral fractures and Small Bone Fixation System, a percutaneous locked intramedullary nail system for metacarpals and the phalanges. The company was founded on June 22, 2004 and is headquartered in Wilmington, DE.

Howmedica Osteonics Corp., a subsidiary of Stryker Corp., is a company headquartered in Mahwah, NJ. The firm manufactures and supplies orthopaedic devices.

Zimmer, Inc. provides joint replacement solutions. The firm products include trauma and dental implants and orthopaedic surgical products. The company was founded in 1927 and is headquartered in Warsaw, IN.

Smith & Nephew PLC designs, manufactures and markets orthopedic devices, sports medicine and ENT technologies, and wound-care solutions. Slightly more than 40% of the U.K.-based firm's revenue comes from orthopedic products, and another 30% is a sports medicine and ENT. The remaining 27% of revenue is from the advanced wound therapy segment. Roughly half of Smith & Nephew's total revenue comes from the United States, just over 30% is from other developed markets, and emerging markets account for the remainder.

Merete GmbH is a German private company located in Berlin that manufactures medical equipment. It was founded in 1996 by Emmanuel Anapliotis. Alexia Anapliotis and Marc Kneissler are the current co-CEOs of the firm.\nThe company says this about itself: Merete GmbH is a manufacturer of implants and endoprostheses in the area of ??hip, foot surgery, bone defects, bone tumors and pediatric orthopedics.

MAKO Surgical is a medical device company, markets its advanced robotic arm solution, joint specific applications for the knee and hip, and orthopedic implants for orthopedic procedures in the United States and internationally. The company offers MAKOplasty, a restorative surgical solution that enables orthopedic surgeons to treat patient specific osteoarthritic disease. It also provides robotic arm interactive orthopedic system (RIO) consisting of a tactile robotic arm utilizing an integrated bone cutting instrument; and a patient specific visualization component, which offers pre-operative and intra-operative guidance to the orthopedic surgeon, enabling tissue sparing bone removal, and accurate implant insertion and alignment. In 2011, The company was named the No.1 on the Technology Fast 500 as the fastest growing technology company by Deloitte and received the CSSEC Award for loyal, customer-focused staff members presented by the Technology Services Industry Association and ACE Award (Achievement in Customer Excellence) from MarketTools and Fast Tech Award as one of the 25 fastest growing technology companies in South Florida by South Florida Business Journal. MAKO Surgical was founded in 2004 and is headquartered in Florida, USA.

Globus Medical, Inc. operates as a medical device company that develops and commercializes healthcare solutions. The firm engages in developing products that promote healing in patients with musculoskeletal disorders. It classifies products into Innovative Fusion and Disruptive Technology. It operates through the United States and International geographical segments. The company was founded by David C. Paul, David D. Davidar and Andrew Iott in March 2003 and is headquartered in Audubon, PA.

Blue Belt Technologies is a medical device company that focuses on technology and capabilities of surgical instrumentation. They proprietary technology can improve minimally invasive techniques in orthopedics, providing physicians with consistency and accuracy through a myriad of intelligent hand-held tools. It also enables the development of more advanced solutions to patients’ problems. Blue Belt Technologies was acquired by Smith & Nephew on January 5m 2016. The company was founded in 2003 and is headquartered in Pennsylvania, USA.

Conformis is a medical technology company that uses its proprietary iFit® Image-to-Implant® technology platform to develop, manufacture, and sell joint replacement implants and instruments that are individually sized and shaped, which it refers to as personalized, individualized, or sometimes as customized, to fit each patient’s unique anatomy. Conformis offers a broad line of sterile, personalized knee and hip implants and single-use instruments delivered to hospitals and ambulatory surgical centers.

OrthoHelix Surgical Designs is a medical device company developing a comprehensive line of implants and instruments for use in small bone reconstructive surgery. OrthoHelix is dedicated to being the most responsive device maker in the orthopedic industry. We provide state of the art extremity fixation products that are reliable and easy to use. We enhance surgical outcomes of patients. Our vision is to be an orthopedic company that succeeds by listening to surgeons, giving them what they want and need for safer, faster, easier surgical procedures and improved patient outcomes. We take pride in upholding values of Integrity, Compliance, Dedication, Focus and Speed. Surgeons Speak.

Innovata Ltd. researches and develops pharmaceutical and medical products. It develops pulmonary products for the treatment of respiratory disorders and other serious diseases. The company was founded on July 20,1987 and is headquartered in Nottingham, the United Kingdom.

Academisch Ziekenhuis Maastricht operates as medical research centre. The company is headquartered in Maastricht, the Netherlands.

DePuy Ireland Unlimited Co., part of Johnson & Johnson, is a company headquartered in County Cork, Ireland. The firm develops and markets diagnostic and therapeutic products.

Part of Einhorn Verwaltungsgesellschaft mbH, Heraeus Medical GmbH is a company headquartered in Wehrheim, Germany, that produces bone cement for joint fixation. Rolft Wetzel and Jan Rinnert are the current co-CEOs of the firm.

Beijing AK Medical Co., Ltd. offers orthopedic products and services. The firm provides surgical instruments and orthopedic products. Beijing AK Medical was founded in May 2003 and is headquartered in Beijing, China.

Howmedica Osteonics Corporation, doing business as Stryker Orthopaedics, develops, manufactures, and distributes orthopedic products and services. It offers hip, knee, upper extremity, trauma, and spinal systems, as well as bone cement and bone substitutes. The company was founded in 1970 and is based in Mahwah, New Jersey. Howmedica Osteonics Corporation operates as a subsidiary of Stryker Corporation.

Designs, manufactures and markets products used musculoskeletal therapy