SantoSolve is developing topical analgesic products based on non-radioactive strontium as the active substance. The Development program was initiated based on experimental clinical use of strontium-based products showing evidence of strong local analgesic effects on several localized pain conditions of both nociceptive and neuropatic origin. No significant adverse effects associated with the treatment was reported. The company’s lead product, 2PX, is topically administered, utilizing dermal penetration enhancers for delivery of the active agent to its subdermal site of action. Phase I safety and pharmacology studies showed the active agent to have low systemic bioavailability, and only few and minor adverse effects were observed at the site of administration. In open label Phase II clinical trials, the product has shown strong analgesic effect in both nociceptive and neuropatic pain conditions. In follow up, placebo controlled trials, the analgesic effect of the product has been further documented. In the company’s most advanced pain indication under study, osteoarthritis, the company has recently completed the Phase II program.These trials supports the open label results and document statistically that the analgesic effect in patients treated with 2PX is superior to that observed with placebo treatment.

Nippon Chemiphar Co., Ltd. engages in the healthcare business. It manufactures, sells, imports, and exports ethical pharmaceuticals and diagnostic agents. It operates through the Pharmaceuticals and Others segments. The Pharmaceuticals segment manufactures and sells prescription drugs. The Others segment includes safety testing consignment, healthcare, and real estate businesses. The company was founded by Akira Yamaguchi on June 16, 1950 and is headquartered in Tokyo, Japan.

Colgate-Palmolive Company (Colgate) is a consumer products company whose products are marketed in over 200 countries and territories throughout the world. It operates in two segments: Oral, Personal and Home Care and Pet Nutrition. Oral Care business products include Colgate Total, Colgate Sensitive Pro-Relief, Colgate Max Fresh, Colgate Optic White, and Colgate Luminous White toothpastes, Colgate 360° manual toothbrushes and Colgate and Colgate Plax mouth rinses. Colgate's Oral Care business also includes dental floss and pharmaceutical products for dentists and oral health professionals. Its Personal Care products also include Palmolive, Softsoap and Sanex brand shower gels, Palmolive, Irish Spring, and Protex bar soaps and Speed Stick, Lady Speed Stick and Sanex deodorants and antiperspirants. It sells liquid hand soap under the Palmolive, Protex and Softsoap brands. Colgate, through its Hill's Pet Nutrition segment (Hill's), manufactures pet nutrition products for dogs and cats.

DePuy Mitek LLC develops, manufactures, and supplies medical devices. Its products include pins, fasteners, suture anchors, and screws. It also offers surgical solutions. It has operations in Raynham, Massachusetts, Neuchatel, Switzerland, and France. The company was founded by Jim Nicholson and Arthur Collias in 1985 and is headquartered in Raynham, MA.

Shenzhen Xuhangsheng Technology Co., Ltd., established on 2019-06-26, Business scope includes general business items:computer database;computer systems analysis;Provide computer technology services;engaged in electronic computer software and hardware,Electronics and Information Technology,electronic product,Technology development in fields such as machinery and equipment,technical consulting,Technical Services,technology transfer;network technology,Communications Engineering,network engineering,Technology development in automotive technology,technology transfer,technical consulting,Technical Services;Biology and Medicine,Bioengineering and Biological Products Development,to develop,Sales;New Chemical Materials,Opto-Mechatronics,Aerospace Ocean and Modern Transportation Equipment,Energy and Environmental Protection,civil nuclear technology,Application of High Technology in Traditional Industries,Development of Printing Technology,to develop,Sales;Engaged in technology development in the field of electromechanical,technical consulting;database service,database management;Business Consulting,Business information consultation,Business Management Consulting,Corporate Image Planning,market research,Market information consultation,marketing planning,Investment information consultation,Investment project planning,Economic Information Consulting;Domestic Trade.,The licensing program is:

Zimmer, Inc. provides joint replacement solutions. The firm products include trauma and dental implants and orthopaedic surgical products. The company was founded in 1927 and is headquartered in Warsaw, IN.

The 301 Hospital (Chinese: 三〇一医院) or People's Liberation Army General Hospital (Chinese: 中国人民解放军总医院), which constitutes simultaneously the PLA Postgraduate Medical School (Chinese: 中国人民解放军医学院), located in Beijing, China, is a military hospital directly subsidiary to Logistic Support Department of the Central Military Commission and the largest general hospital under the auspices of the People's Liberation Army. Its mission includes assuring the health of PLA and China's leaders.

Bio Dynamics is a provider of products for patients with obesity, sedentary patients.

Guided Therapy Systems develops and commercializes products that combine ultrasound imaging with intense therapeutic ultrasound, offering physicians the unprecedented ability to image and treat with the same equipment, thus targeting and evaluating tissue prior, during and after a procedure.

Shanghai Huoer Biotechnology Co., Ltd., established on 2016-10-08, Business scope includes technology development in the field of biotechnology,Technical Services,technology transfer,technical consulting(remove human stem cells,Development and application of genetic diagnosis and treatment technology),medicine,Health products,food research and development,Engaged in the import and export of goods and technology,food circulation. [Items subject to approval by law,Business activities can only be carried out after approval by relevant departments]

Smith & Nephew PLC designs, manufactures and markets orthopedic devices, sports medicine and ENT technologies, and wound-care solutions. Slightly more than 40% of the U.K.-based firm's revenue comes from orthopedic products, and another 30% is a sports medicine and ENT. The remaining 27% of revenue is from the advanced wound therapy segment. Roughly half of Smith & Nephew's total revenue comes from the United States, just over 30% is from other developed markets, and emerging markets account for the remainder.

DePuy Synthes Products, Inc. develops and markets medical products. It offers distal volar Radius, which is designed to treat distal radius fractures, dorsal endoplate, an invasive dorsal nail plate that provides fixed angle support and intramedullary locked fixation with a duplicate and reproducible surgical procedure, spatial subchondral support plate, which is used to treat proximal humeral fractures and Small Bone Fixation System, a percutaneous locked intramedullary nail system for metacarpals and the phalanges. The company was founded on June 22, 2004 and is headquartered in Wilmington, DE.

Ethicon, Inc. is a subsidiary of Johnson & Johnson. It was incorporated as a separate company under the Johnson & Johnson umbrella in 1949 to expand and diversify the Johnson & Johnson product line. Ethicon has manufactured surgical sutures and wound closure devices since 1887. After World War II, Ethicon's market share in surgical sutures rose from 15% to 70% worldwide. In the United States, the market share is approximately 80%.

Shenyang Shangxian Minimally Invasive Medical Devices Co., Ltd., established on 2010-12-08, Business scope includes production and sales of medical devices(The specific business scope is subject to the license);Medical device research and development,Scientific Instruments,electronic product,Software product development and sales,Self-operated and agent import and export of various commodities and technologies,Except for the goods and technologies that the state restricts the company to operate or prohibits the import and export of.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments.)

Frabo SRL is a private company headquartered in Italy that wholesales haberdashery, packages and clothes.

Zhengzhou Feilong Medical Equipment Co., Ltd., established on 2005-09-12, Business scope includes licensed projects:Production of Class II Medical Devices;Class III medical device business(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments,The specific business items are subject to the approval documents or licenses of relevant departments)General project:Sales of Class II Medical Devices;Class II Medical Device Leasing;Technical Services,technology development,technical consulting,Technology Exchange,technology transfer,Technology Promotion;Wholesale of computer software, hardware and auxiliary equipment;Instrument sales;Import and export;Technology Import and Export;Mechanical and electrical equipment manufacturing;Sales of mechanical and electrical equipment;electronic,Mechanical equipment maintenance(No special equipment);General machinery and equipment installation services;Sales of electronic components and electromechanical components;Refrigeration,Air Conditioning Equipment Manufacturing;Refrigeration,Air Conditioning Equipment Sales;Pension Service;furniture sales;needle textile sales;Wholesale of sporting goods and equipment(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license)

Sinopharm Dezhong (Foshan) Pharmaceutical Co., Ltd. is a pharmaceutical company in China. It offers herbal formulated medicine in forms of pills, tablets, creams & syrup. The company was founded in November 1998 and is headquartered in Guangdong, CN.

Beijing Dongyue Runqi Medical Technology Development Co., Ltd., established on 2013-09-06, Business scope includes general items:Technical Services,technology development,technical consulting,Technology Exchange,technology transfer,Technology Promotion;Sales of Class I Medical Devices;Sales of Class II Medical Devices;Wholesale of computer software, hardware and auxiliary equipment;Retailing of computer software, hardware and auxiliary equipment;hospital management;hotel management;Supply Chain Management Services;food delivery service;Medical Research and Experimental Development;Health Consulting Services(Does not include medical services);Natural science research and experimental development;Wholesale of sporting goods and equipment;Sporting Goods and Equipment Retailing;Personal Hygiene Sales;Sales of hygiene products and single-use medical products;Daily necessities sales;Arts and crafts and etiquette supplies sales(Except for ivory and its products);Stationery retail;Chemical product sales(No licensed chemical products);Daily miscellaneous goods sales;General merchandise sales;Home Appliance Sales;Cosmetics Wholesale;Cosmetics Retail;Sales of daily chemical products;Wholesale Jewelry;Jewelry Retail;Sales of knitted textiles and raw materials;Clothing and apparel wholesale;Sales of clothing accessories;Clothing and apparel retail;furniture sales;gift flower sale;Wholesale of aquatic products;Aquatic product retail;Fresh Meat Wholesale;Fresh Meat Retail;Retailing of Edible Agricultural Products;Wholesale of edible agricultural products;Leather Goods Sales;Crop Seed Management(Packaged seeds no longer in packs only);Data processing and storage support services;data processing services;Machinery and Equipment Leasing;Machinery sales;Computer and communication equipment rental;Etiquette service;Socioeconomic Advisory Services;Project planning and public relations services;Corporate Image Planning;advertising;Advertising Design,acting;advertisement making;marketing planning;Consulting and planning service;Conference and Exhibition Services;entertainment exhibition;Calculator Equipment Sales.(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license)licensed items:Radio and television program production and management;Drug internet information service;The second type of value-added telecommunications services;Class III medical device business.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments,The specific business items are subject to the approval documents or licenses of relevant departments)(Do not engage in the business activities of projects prohibited and restricted by the industrial policies of the state and this city.)