Medtronic, Inc. operates as a medical technology company. It offers implantable cardiac pacemakers, eternal defibrillators, inferior turbinate surgery products, and continuous glucose monitoring device. The company was founded by Earl E. Bakken and Palmer J. Hermundslie on April 29, 1949 and is headquartered in Minneapolis, MN.

Cardiac Pacemakers, Inc.(CPI), doing business as Guidant Cardiac Rhythm Management, manufactured implantable cardiac rhythm management devices, such as pacemakers and defibrillators. It also sold insulin pumps controlled by microprocessors and various equipments to regulate heart rhythm. In addition, Cardiac Pacemakers, Inc. developed therapies for the treatment of irregular heartbeats. The company was founded in 1971 and is based in St. Paul, Minnesota. Cardiac Pacemakers, Inc. operates as a subsidiary of Boston Scientific Corporation.

Pacesetter, Inc., a subsidiary of Abbott Laboratories, is a company headquartered in the United States that manufactures, and distributes cardiovascular and implantable neuro stimulation medical devices.

Lungpacer Medical is developing a novel therapeutic solution for preserving the integrity and strength of the diaphragm muscle The objective of the company is to develop and commercialize a novel therapeutic solution that addresses the significant health and cost issues associated with mechanical ventilation of critically ill patients in hospital Intensive Care Units (ICU). It is designed to activate the diaphragm using a temporary, minimally invasive, transvascular nerve stimulation approach that is expected to save many lives, improve surviving patient outcomes and greatly reduce hospital care costs. In addition, the paced diaphragm is expected to restore negative pressure ventilation, thereby potentially providing a more physiological respiratory pattern and reducing the levels of positive pressure ventilation and its harmful effects on the lungs. Lung Pacer was founded in 2009 and is headquartered in Vancouver, British Columbia, Canada.

UAB Research Foundation (doing business as UABRF), a subsidiary of The University of Alabama System, is a company headquartered in Birmingham, AL. The firm engages in identify, assess, and market commercially viable technology developed at The University of Alabama at Birmingham.

Bard Access Systems, Inc. develops, manufactures and distributes medical devices. It makes vascular access products as dialysis & pheresis catheters, implanted ports, ultrasound systems and surgical accessories. The company was founded in 1947 and is headquartered in Salt Lake City, UT.

Edwards Lifesciences Corp. engages in patient-focused medical innovations for heart disease and critical care monitoring. Its products are categorized into four main areas: Transcatheter Aortic Valve Replacement, Transcatheter Mitral and Tricuspid Therapies, Surgical Structural Heart, and Critical Care. It operates through the following geographical segments: United States, Europe, Japan, and Rest of World. The company was founded by Miles Lowell Edwards in 1958 and is headquartered in Irvine, CA.

The Board of Regents of The University of Texas System, a subsidiary of The University of Texas at Austin, is an American company located in Austin, TX. The firm oversees college activities.

St. Jude Medical, Inc. was an American global medical device company headquartered in Little Canada, Minnesota, U.S., a suburb of Saint Paul. The company had more than 20 principal operations and manufacturing facilities worldwide with products sold in more than 100 countries. Its major markets include the United States, Europe, Latin America and Asia-Pacific. The company was named after Jude the Apostle, the patron saint of lost causes.

3F Therapeutics develops, manufactures, and markets cardiovascular devices. It offers invasive and transapical aortic heart replacement technology, including enabling aortic heart valve, entrata aortic valve system, and endurance valve system to reduce surgical cross-clamp and cardio-pulmonary bypass time, utilization for congestive heart failure.

Zoll Circulation, Inc., a subsidiary of Asahi Kasei Corp., is an American company. The firm manufactures cardiac resuscitation devices.

Heartport is an entrepreneurial medical device maker that has introduced several innovative systems for conducting less-invasive cardiac surgery. The company was founded by John H. Stevens and Wesley D. Sterman. Heartport manufactures and markets less invasive cardiac surgery products that enable surgeons to perform a wide range of less invasive open-chest and minimally invasive heart operations, including stopped heart and beating heart procedures. In April 2001, Heartport was merged with and into CARDIOVATIONS, a wholly-owned subsidiary of Johnson & Johnson. Heartport continues to operate as a part of the division of Ethicon, Inc., a Johnson & Johnson company. Ethicon is a global leader in developing and marketing products for surgery in the areas of wound closure and wound management, surgical sports medicine, women's health and cardiovascular surgery.

Penumbra, Inc. develops clinically beneficial products that help patients suffering from stroke and other neurovascular diseases. It offers Penumbra System, an ischemic stroke device platform; Penumbra Coil 400 that allows rapid packing of aneurysms; 5MAX ACE, a clot extraction device for engaging and removing blood clots causing an acute ischemic stroke; and Neuron System, a family of access catheters to enable therapies to be delivered to blood vessels high up in the brain. The company sells its products in North and South America, Europe, Australia, and Asia. Penumbra, Inc. was founded in 2004 and is headquartered in Alameda, California.

Advanced Cardiovascular Systems, Inc. develops and manufactures cardiovascular medical products. It operates as a subsidiary of Abbott Laboratories. Its medical devices help patients with heart diseases in returning to active and productive lives and physicians for improving patient management and clinical outcomes. Advanced Cardiovascular Systems, Inc. is based in Santa Clara, California. it is currently known as Abbott Cardiovascular Systems.

Protaryx Medical, Inc. is a medical device company, which develops differentiated transseptal access device that is itended for crossing the atrial septum of the heart to improve, streamline, and facilitate catheter-based. minimally invasive left heart interventional therapies. The company was founded by Terri Burke and James S. Gammie and is headquartered in Baltimore, MD.

Interventional Autonomics Corp. is a private company headquartered in the United States. The firm supplies pharmaceutical products. It was founded in 2008 by William N. Starling.