Edwards Lifesciences Corp. engages in patient-focused medical innovations for heart disease and critical care monitoring. Its products are categorized into four main areas: Transcatheter Aortic Valve Replacement, Transcatheter Mitral and Tricuspid Therapies, Surgical Structural Heart, and Critical Care. It operates through the following geographical segments: United States, Europe, Japan, and Rest of World. The company was founded by Miles Lowell Edwards in 1958 and is headquartered in Irvine, CA.

Signpath Pharma is a development stage biotechnology company founded in 2006. Its lead compound is 99.2% pure synthesized curcumin (diferuloylmethane). Curcumin has an extensive and long history in humans as a mixture of naturally occurring curcuminoids in extracts of the root of the Curcuma longa plant. Traditional use of curcumin has been restricted to topical skin and gastrointestinal conditions because of negligible absorption when given orally. To extend its clinical use Signpath is developing three different intravenous nanoparticle-sized formulations; liposomal, polymeric, and PLGA. Proof of efficacy of these formulations against human tumor xenografts in mice has been established. Following intravenous injection of each formulation, we observed transport across the blood brain barrier in mice, rats, and localization in the hippocampus, brainstem and the striatum.

Caisson Interventional is a privately held clinical-stage medical device company focused on the design, development, and clinical evaluation of a novel percutaneous mitral valve replacement system.

VisCardia, Inc. develops and manufactures medical devices. The firm investigates a novel therapy for improving hemodynamic function to manage medical refractory heart failure. The company was founded in 2015 and is headquartered in Beaverton, OR.

Coroneo develops novel cardiac implants for aortic valve repair. Their repair technology provides an invasive alternative to valve replacement with a prosthetic heart valve. Their COR-VALV system provides valve exposure during cardiac surgery with adjustable tissue retractors. They design the swivel blade that allows displacement of the rack bar during use for enhanced surgical access to the thoracic cavity.

ACIST is a pioneering interventional and diagnostic technology company with a portfolio of advanced products, including the world’s first Rapid Exchange FFR and High Definition IVUS systems. They are also a global market leader in advanced contrast imaging systems for cardiovascular angiography. As part of the Bracco Group, ACIST benefits from the resources of a multinational conglomerate with broad expertise in cath lab technology and a dedication to continuous advancement. At every level of their operations, they are focused on their shared vision to be a leading provider of innovative diagnostic and interventional products and services that enable the interventionalist and their clinical team in providing superior patient care.

Terumo is a global leader in medical technology and has been committed to "Contributing to Society through Healthcare.

Esaote SpA is a holding company, which engages in the production of medical diagnostic systems. Its products include ultrasound system applications, dedicated magnetic resonance imaging (MRI) systems, healthcare information technology software applications, and interventional and mini-invasive system applications under the brand name Esaote. The company was founded by Carlo Castellano in 1982 and is headquartered in Genoa, Italy.

For over 25 years, SunTech Medical has been the preeminent supplier of clinical grade blood pressure monitoring products and technologies. Over 75 companies trust SunTech Medical's OEM non-invasive blood pressure solutions for their patient monitoring needs. SunTech Medical produces the leading cardiac stress test blood pressure monitor and is the world's foremost manufacturer of ambulatory blood pressure monitoring (ABPM) products. SunTech Medical also offers solutions for in-office blood pressure monitoring as well as a complete line of blood pressure cuffs designed for general and specific applications.

Manufactures healthcare equipment

Acarix A/S is based on pioneering research performed at the Aalborg University, Denmark, initiated in 2004. The research group received the award, ‘MedicoPrisen’, from Medicoindustrien (Danish Medtech trade association) in 2007. A research and development collaboration was established in 2007 between Aalborg University and Coloplast A/S, receiving public support from the Danish National Advanced Technology Foundation in 2008. Acarix A/S was established in 2009 as a spin-out company from Coloplast A/S with Coloplast A/S and Aalborg University as the major shareholders. In 2010 Acarix A/S succeeded attracting venture capital from Seed Capital (DK), Sunstone Capital (DK) and Seventure Partners (F). In 2011 Acarix A/S and collaborators furthermore achieved funding of 5.3 million DKK from the Danish Business Innovation Fund.

HeartWare, Inc. manufactures electro medical and electrotherapeutic apparatus. The company develops implantable circulatory assist devices, which are used in treating patients with congestive heart failure problems. The company was established in 2003 and is headquartered in Miramar, FL

TC1 LLC, part of Abbott Laboratories, is a company headquartered in the United States that manufactures blood pressure apparatus.

Assistance Publique des Hôpitaux de Paris SA the company is headquartered in Paris, France.

Qingdao Hisense Medical Equipment Co., Ltd., established on 2014-02-28, Business scope includes licensed projects:medical service;Class III medical device business;Class III Medical Device Leasing;Production of Class III Medical Devices;Production of Class II Medical Devices;Internet Information Service for Medical Devices;Construction engineering design;Construction Engineering Construction;Disinfection equipment sales.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments,The specific business items are subject to the approval documents or licenses of relevant departments)General project:Special Equipment Repair;Sales of Class II Medical Devices;Class II Medical Device Leasing;Sales of Class I Medical Devices;Class I Medical Device Leasing;Production of Class I Medical Devices;Manufacturing of special equipment(Manufacture of licensed professional equipment not included);Import and export;Machinery and Equipment Leasing;software development;Engineering and Technology Research and Experimental Development;Technical Services,technology development,technical consulting,Technology Exchange,technology transfer,Technology Promotion;Health Consulting Services(Does not include medical services);Manufacturing of computer software, hardware and peripheral equipment;IoT application service;5GCommunication Technology Services;Information Technology Consulting Services;Information system integration service;Artificial intelligence public service platform technical consulting services;Artificial intelligence public data platform;Artificial intelligence industry application system integration service;Internet of things technology research and development;Refrigeration,Air Conditioning Equipment Sales;Sales of mobile terminal equipment.(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license)

Romano Srl is an Italian private company located in Lanciano. The firm operates as new and used car dealers.