Headquartered in Morrisville, North Carolina, TearScience has pioneered devices that provide significant clinical identification and treatment of evaporative dry eye. Of the 100 million plus of dry eye sufferers worldwide, the leading cause (86percent) is evaporative dry eye, which is caused by Meibomian Gland Dysfunction (MGD) and a lipid deficiency of the eye’s natural tear film. The Tear Film and Ocular Surface Society (TFOS) workshop, involving two years of work by 50 leading experts from around the world, concluded that MGD is an under-estimated condition and is very likely the most frequent cause of dry eye disease. Common symptoms of the disease include eye irritation, dryness, redness, tiredness, and visual disturbances. TearScience’s integrated, in-office system enables eye care professionals to effectively address a root cause of evaporative dry eye.

AxeroVision, Inc., part of Chuangsheng Qiao Kang Pharmaceutical Co. Ltd., is a company headquartered in Carlsbad, CA. The firm develops therapies for the treatment of Dry Eye Disease (DED) and other ophthalmic inflammatory problems. It was founded in 2016 by Achim Krauss, who has been the CEO since the company founding. On July 28, 2023 Chuangsheng Qiao Kang Pharmaceutical Co. Ltd. acquired AxeroVision, Inc.

Santen Pharmaceutical Co., Ltd engages in the manufacture and sale of pharmaceutical products and medical devices. It operates through the following segments: Pharmaceuticals and Others. The Pharmaceuticals segment includes prescription ophthalmic drugs, anti-rheumatic pharmaceuticals, and over-the-counter products. The Others segment offers medical equipment and devices. The company was founded by Kenkichi Tagushi in 1890 and is headquartered in Osaka, Japan.

Part of MOH Holdings Pte Ltd., Singapore Health Services Pte Ltd. is a Singaporean company located in Singapore. The firm provides medical services. Ivy Ng is the CEO, in this role since 2012.

Senju Pharmaceutical Beijing Co. Ltd., part of Senju Pharmaceutical Co., Ltd., is a company headquartered in Beijing, China, that manufactures and distributes pharmaceuticals.

Oculeve is a start-up MedTech company with a first-in-class connected health technology to address an unmet clinical need in ophthalmology. Early investors included KPCB, NEA, and Versant. In August 2015, Oculeve was acquired by Allergan Plc.

Novaliq is a pharmaceutical company focusing on the development and commercialization of first- and best-in-class ocular therapeutics based on EyeSol®, the first and only water-free technology worldwide for ophthalmology products. With an initial focus on dry eye disease (DED), Novaliq offers an industry-leading portfolio addressing today’s unmet medical needs of millions of patients with eye diseases. Two EyeSol® entities have been developed to distinctly target either predominantly aqueous or evaporative disease and potentially break the vicious circle of DED. Both are currently in phase 3 development: >> NOV03 (100% perfluorohexyloctane) is the first drug developed to treat evaporative DED associated with Meibomian gland dysfunction in a highly effective way. >> CyclASol®, an ophthalmic solution of 0.1% cyclosporine A in EyeSol®, is an anti-inflammatory and immunomodulating drug for the treatment of aqueous deficient DED. Both investigational drugs have shown superior clinical benefit, with an early onset of action and an excellent tolerability profile. NovaTears® water-free eye drops for dry eye disease have CE Marking and are commercialized in Australia/New Zealand by AFT Pharmaceuticals and in Europe as EvoTears® by Ursapharm. Novaliq is headquartered in Heidelberg, Germany and has an office in Cambridge, MA, USA. The long-term shareholder is dievini Hopp BioTech Holding, an active investor in Life and Health Sciences companies. More on www.novaliq.com.

Tianjin Haihe Hospital Co., Ltd., established on 2003-05-15, Business scope includes internal medicine,surgery,Gynecology,Pediatrics,ENT,Chinese Medicine,Oncology,Dermatology,Medical Cosmetology.(If the state has special franchise regulations, it shall be implemented in accordance with the regulations)(For those that require pre-approval in the business scope, the approval document and approval time limit shall prevail)

Sight Sciences is a medical device company that uses a computer-based device designed for the treatment of eye disease. Sight Sciences' devices and non-invasive dry eye products are used for glaucoma procedures or in combination with cataract surgery using the same clear corneal incision, assisting ophthalmologists and optometrists to address the underlying physiology of ophthalmic disease. The company's non-surgical Dry Eye product portfolio consists of TearCare which is now commercially available for both ophthalmologists and optometrists. TearCare is a software-controlled, wearable eyelid technology that delivers highly targeted and adjustable heat to the meibomian glands of the eyelids for conditions such as meibomian gland dysfunction and dry eye. It was founded in 2011 and is headquartered in Menlo Park, California, United States.

Tianjin Weiju Technology Co., Ltd., established on 2014-08-13, Business scope includes general items:Technical Services,technology development,technical consulting,Technology Exchange,technology transfer,Technology Promotion;Advertising Design,acting;advertisement making;advertising;Health Consulting Services(Does not include medical services);Business Management Consulting;Information Consulting Service(Not including licensing information consulting services);software development;Wholesale of computer software, hardware and auxiliary equipment;Sales of industrial control computers and systems;Rehabilitation assistive device fitting service;Sales of Class II Medical Devices;food sales(Only sell prepackaged food);Cosmetics Retail;General merchandise sales;Disinfectant sales(Free of Hazardous Chemicals);Personal Hygiene Sales.(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license)licensed items:Class III medical device business.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments,The specific business items are subject to the approval documents or licenses of relevant departments)

Nippon Chemiphar Co., Ltd. engages in the healthcare business. It manufactures, sells, imports, and exports ethical pharmaceuticals and diagnostic agents. It operates through the Pharmaceuticals and Others segments. The Pharmaceuticals segment manufactures and sells prescription drugs. The Others segment includes safety testing consignment, healthcare, and real estate businesses. The company was founded by Akira Yamaguchi on June 16, 1950 and is headquartered in Tokyo, Japan.

Peking University Third Hospital is a private company headquartered in Beijing, China, that operates as a clinic.

Zhejiang Angel Eye Technology Co., Ltd., established on 2015-04-21, The business scope includes eye protectors,Eye protector,Electric eyewash,eye massager,beauty equipment,Health massage equipment,Development of an eye movement machine,production and sales;cosmetic,hygiene products,cleaning supplies,electronic product,R&D of hardware products;Class I medical device,Manufacture of Class II Medical Devices,Processing and sales;cosmetic,hygiene products,cleaning supplies,Disinfection supplies,disinfectant,Sports Equipment,electrical equipment,electronic product,Wujinjiaodian,daily necessities,outdoor equipment,Stationery,kids toys,Online sales and wholesale of clothing, shoes and hats,retail;Fashion Design;window design;Self-operated or agent import and export of goods and technologies,Except for goods and technologies that are restricted or prohibited from being imported or exported by the state.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments)

Zhejiang Garden Runjia Medical Equipment Co., Ltd., established on 2019-01-11, The scope of business includes the first,Production of Class II Medical Devices,Sales.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments)

Longhua Hospital Shanghai University of TCM, a subsidiary of Shanghai University of Traditional Chinese Medicine, is a company headquartered in Shanghai, China. The firm provides hospital services.

Hangzhou Upyun Technology Co. Ltd. provides one-stop cloud acceleration services for customers and helps them to solve the problems of data storage, processing and acceleration, thus access to the cloud rapidly and driving startup companies faster forward. It expertise's in CDN+Cloud service mode. The company was founded by Pingyang Liu in 2010 and is headquartered in Hangzhou, China.

Alcon, Inc. engages in the development, manufacture, and marketing of market surgical equipment and devices, pharmaceutical eye drops, and consumer vision care products to treat eye diseases and disorders. It operates through the following segments: Surgical and Vision Care. The Surgical segment offers implantable products, consumables and equipment for use in surgical procedures to address cataracts, vitreoretinal conditions, refractive errors, and glaucoma. The Vision Care segment comprises daily disposable, reusable and color-enhancing contact lenses, as well as portfolio of ocular health products, including over-the-counter products for dry eye, contact lens care, and ocular allergies, as well as ocular vitamins and redness relievers. The company was founded by Mr. Robert Alexander and Mr. William Conner on 1945 and is headquartered in Geneva, Switzerland.

Lumenis Ltd. engages in provision of minimally-invasive clinical solutions. It specializes in urology, eye care, women's health, head and neck, orthopedics, pulmonary and thoracic, and gastroenterology. It also offers aesthetics treatments such as hair removal, body, skin, pigmentation, scars, tattoo removal, vascular lesions, and others. he company was founded on December 21, 1991 and is headquartered in Yokneam Illit, Israel.

Industry Academic Cooperation Foundation Hallym University is a private company headquartered in the South Korea. The firm provides office support services.

Chengdu Jiaborui Medical Equipment Co., Ltd., established on 2021-08-12, Business scope includes general items:Sales of Class I Medical Devices;Production of Class I Medical Devices[Branch operation];Sales of Class II Medical Devices.(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license)