Thebaine (paramorphine), also known as codeine methyl enol ether, is an opiate alkaloid, its name coming from the Greek Θῆβαι, Thēbai (Thebes), an ancient city in Upper Egypt. A minor constituent of opium, thebaine is chemically similar to both morphine and codeine, but has stimulatory rather than depressant effects. At high doses, it causes convulsions similar to strychnine poisoning. The synthetic enantiomer (+)-thebaine does show analgesic effects apparently mediated through opioid receptors, unlike the inactive natural enantiomer (−)-thebaine. While thebaine is not used therapeutically, it is the main alkaloid extracted from Papaver bracteatum (Iranian opium / Persian poppy) and can be converted industrially into a variety of compounds, including oxycodone, oxymorphone, nalbuphine, naloxone, naltrexone, buprenorphine and etorphine. Butorphanol can also be derived from thebaine.
Tasmanian Alkaloids Pty Ltd.
http://www.extractas.com.au
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Tasmanian Alkaloids is a fully-integrated manufacturer of controlled substances providing medicinal opiates from patented poppy varieties grown on the farms of Tasmania. The people of this enterprise, at the factory and on the farms, are committed to the highest quality standards and good manufacturing practice. They are committed to ensuring that our long-term business partners receive a fully reliable supply of our product.
Pharmaceutical manufacturing
Agriculture
Alkaloid
Poppy
Opiate
Good manufacturing practice
Quality standard
Reckitt & Sons Ltd., part of Reckitt Benckiser Group Plc, is a company headquartered in Slough, UK. The firm provides financial services. It was founded in 1956.
Palla Pharma Ltd.
http://www.tpienterprises.com
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TPI Enterprises manufactures and supplies alkaloids in Australia and internationally.
Its products include the concentrate of poppy straw morphine, thebaine, oripavine, and codeine; technical morphine, thebaine, oripavine, and codeine; noscapine; alkaloid impurities; and 14-hydroxy and nor- derivatives.
The company also sells and exports culinary poppy seeds. It supplies narcotic raw materials, primarily morphine and thebaine to pharmaceutical companies participating in the active pharmaceutical ingredient sector.
Pharmaceutical manufacturing
Medicine
Thebaine
Good manufacturing practice
Oripavine
Codeine
Alkaloid
Poppy straw
Noscapine
Poppy seed
Poppy
Impurity
Raw material
Cody Laboratories, Inc., a subsidiary of Lannett Co., Inc., is a company headquartered in Cody, WY, that manufactures pharmaceutical products. The firm was acquired by Lannett Co., Inc. on April 10, 2007 for $4.44 million.
Pain-relief Medication
Food industry
Medicine
Good manufacturing practice
Dosage form
Pharmaceutical manufacturing
Contract research organization
Coating
Johnson Matthey is an international speciality chemicals company, founded almost 200 years ago in London. Technology leadership forms the basis of our strategy to deliver superior long term growth
Diesel particulate filter
Chemical engineering
Cisco Catalyst
Speciality chemicals
Gasoline
Metal
Precious metal
Palladium
Platinum
Diesel engine
Cathode material
Exhaust gas recirculation
Selective catalytic reduction
Catalytic converter
Automotive catalyst
Lithium-ion battery
Ruthenium
Rhodium
Lead–acid battery
MacFarlan Smith Ltd.
http://macsmith.lookchem.com
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MacFarlan Smith Ltd. is a company headquartered in Edinburgh, UK, that manufactures pharmaceutical products. It was founded in 1960.\nThe company says this about itself: Founded in 1815, Macfarlan Smith Limited is one of the world's oldest pharmaceutical companies, with almost 200 years of expertise in natural product extractions and chemical synthesis, specialising in opiate narcotics such as codeine and morphine. Over the past two centuries, we have collaborated with Lord Lister, supplied chloroform to Sir James Simpson, and produced the first liquid essence of coffee. Today, as part of Johnson Matthey PLCs Fine Chemicals Division, the company operates a state-of-the-art plant to the highest level of cGMP. We are the world's leading manufacturer of opiate alkaloids and together with our sister companies, Johnson Matthey Pharmaceutical Materials (NJ, USA) and Johnson Matthey Pharma Services (MA, USA) we are able to provide the full spectrum of development, from drug discovery through to bulk production.
Medicine
Pharmaceutical manufacturing
Opiate alkaloid
Good manufacturing practice
Codeine
Chloroform
Narcotic
Opiate
Contract research organization
Chemical synthesis
Remifentanil
Natural product
Drug discovery
Anesthetic
Travatan Z
Active ingredient
Dosage form
Coating
Precigen, Inc. is a biotechnology company, which engages in the research and development of synthetic biology technologies. It operates through the following segments: Biopharmaceuticals, Exemplar, and Trans Ova. The Biopharmaceuticals segment is involved in advancing the next generation of gene and cell therapies using precision technology to target urgent and intractable diseases in immuno-oncology, autoimmune disorders, and infectious diseases. It also engages in pioneering a proprietary class of microbe-based biopharmaceuticals that enable expression and local delivery of disease-modifying therapeutics. The Exemplar segment is focused on developing research models and services for healthcare research applications. The Trans Ova segment provides bovine reproductive technologies. The company was founded by Thomas David Reed in 1998 and is headquartered in Germantown, MD.
Cell therapy
Biology
Pharmacy and Therapeutics
Synthetic biology
Biotechnology
Genomics
Bioconversion
Reproductive technology
Biological system
Drug discovery
Toxicity
Methane
Gene
Biopharmaceutical
CRISPR
Control system
Cell
RNA
Mesenchymal stem cell
Purdue Pharma LP
http://www.purduepharma.com
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Purdue Pharma L.P. is a privately held pharmaceutical company owned principally by descendants of Mortimer and Raymond Sackler. In 2007, it paid out one of the largest fines ever levied against a pharmaceutical firm for mislabeling its product OxyContin, and three executives were found guilty of criminal charges. Although the company shifted its focus to abuse-deterrent formulations, Purdue continued to market and sell opioids, and continued to be involved in lawsuits around the opioid epidemic in the United States. Purdue filed for Chapter 11 bankruptcy protection on September 15, 2019 in New York.
Opioid
Medicine
Opioid epidemic
Analgesic
Methadone
Neuropathic pain
Morphine
Oxycodone
Substance abuse
Hydrocodone
Addiction
Biomedicine
Codeine
Biotechnology
Cannabis
Alcohol dependence
Pethidine
Buprenorphine
Gastrointestinal agent
Zentiva ks specializes in the development, manufacture and marketing of generic pharmaceutical products. It offers generic drugs, over the counter medicines, dietary supplements, cosmetics and pharmaceutical substances. The company's products cover therapy areas of cardiovascular disease, pain, alimentary, genitourinary tract diseases, inflammations and central nervous system diseases including digestive problems. Zentiva was founded in 1989 and is headquartered in Prague, Czech Republic.
Prescription drug
Medicine
Generic drug
Central nervous system
Inflammation
Cosmetics
R.P. Scherer GmbH & Co. KG
R.P. Scherer GmbH & Co. KG, part of Catalent, Inc., is a company headquartered in Eberbach, Germany, that develops, manufactures and sells pharmaceutical products.
Reckitt Benckiser Healthcare (UK) Ltd.
Reckitt Benckiser Healthcare (UK) Ltd., a subsidiary of Reckitt Benckiser Group Plc, is a British company located in Slough. The firm manufactures household and sanitary goods. It was founded in 1931.\nThe company says this about itself: The principal activity of the company which is a Member of the Reckitt Benckiser group of companies is the manufacture and sale of branded consumer products for sale to other Group companies.
Saneca Pharmaceuticals AS
Saneca Pharmaceuticals AS is a Slovak (SK*) private company located in Hlohovec. The firm provides pharmaceutical services.
Medicine
Active ingredient
Pharmaceutical manufacturing
Biobank
Microarray
Cell signaling
Exosome
Biomedicine
Biotechnology
Rohm and Haas Company is a manufacturer of speciality chemicals for end use markets such as building and construction, electronic devices, packaging, household and personal care products. Headquartered in Philadelphia, the company is organised into three business groups of Specialty Materials, Performance Materials and Electronic Materials, and also has two stand-alone businesses of Powder Coatings and Salt. Formerly a Fortune 500 Company, Rohm and Haas employs more than 17,000 people in 27 countries, with its last sales revenue reported as an independent company at US$8.9 billion. Dow Chemical Company bought Rohm and Haas for $15 billion in 2009.
Adhesive
Agriculture
Coating
Synthetic rubber
Silicon carbide
Pastry
Ion-exchange resin
Isophorone diisocyanate
Rare-earth magnet
Superhard material
Tungsten carbide
Neodymium magnet
Butyl acrylate
Smart material
Magnet
Ethyl acrylate
Acrylic acid
Chocolate confectionery
Abrasive
Powder coating
Part of Indivior PLC, Indivior UK Ltd. is a company headquartered in Hull, UK, that manufactures and distributes pharmaceutical products. It was founded in 2010.
C.H. Boehringer Sohn AG & Co. KG
http://unternehmensbericht.boehringer-ingelheim.de
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C.H. Boehringer Sohn AG & Co. KG operates as a holding company, with interests in the manufacturing of pharmaceutical products. It offers prescription drugs for the treatment of human respiratory, cardiovascular, gastrointestinal, and central nervous system diseases, including human immunodeficiency virus infection and cancer. The company was founded in 1885 and is headquartered in Ingelheim am Rhein, Germany.
Medicine
Human immunodeficiency virus (HIV)
Human immunodeficiency
Central nervous system
Insulin aspart
Prescription drug
Monoclonal antibody
Dulaglutide
Zoonosis
Biopharmaceutical
Insulin
Biguanide
Cardiovascular agent
Liraglutide
Anticoagulant
Biotechnology
Insulin glulisine
Dapagliflozin
Insulin glargine
Pulmonary medicine
Antheia is a biotechnology company unlocking the medicinal power of nature with its rapid response biomanufacturing processes for essential medicines.
Antheia uses synthetic biology to surpass the limits of conventional drug manufacturing and discovery. By reconstructing complex molecules in yeast, Antheia can produce APIs without the use of medicinal plants, transforming the pharmaceutical supply chain and ensuring reliable, consistent, and widespread availability to essential medicines.
Synthetic biology
Medical equipment
Medicine
Fermentation
Informatics
Metabolic engineering
Industrial biotechnology
Intellectual property
Third generation sequencing
Plasmid
Microarray
Microfluidics
Biotechnology
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