Ultrazonix DNT AB develops medical equipment for the treatment of spinal disorders. It offers non-invasive sono-thermal devices for treating patients with chronic degenerative disc disease and prolapsed discs. The company was founded in December 1998 and is headquartered in Lund, Sweden.

Guided Therapy Systems develops and commercializes products that combine ultrasound imaging with intense therapeutic ultrasound, offering physicians the unprecedented ability to image and treat with the same equipment, thus targeting and evaluating tissue prior, during and after a procedure.

FlowCardia, Inc. is a medical device company founded in 2002 to design and develop a portfolio of innovative, catheter-based technologies to facilitate guidewire crossing of totally occluded coronary and peripheral arteries. Chronic Total Occlusions (CTOs) are considered one of the last major clinical challenges in interventional therapy. The historic absence of safe and effective CTO recanalization devices is a major reason a large number of patients are still referred to coronary and peripheral bypass surgery and lower limb amputation.

Pharmasonics develops, manufactures and plans to market power ultrasonic interventional cardiology devices to address the problem of restenosis in coronary arteries. Their lead product aims to reduce the rate of restenosis after intervention by applying a therapeutic level of ultrasound radiation to the target lesion

ImaRx Therapeutics, Inc. manufactures biopharmaceutical products. The company develops and manufactures therapies for vascular disorders associated with blood clots based on two programs, thrombolytics and sonoLysis. Its therapeutics products are approved by the US Food, Drug Administration and FDA, for the treatment of acute pulmonary embolism or blood clots in the lungs. The company was founded in 1991 and is headquartered in Los Angeles, CA

Decision Sciences Medical is transforming Advanced Medical Imaging for diagnosing and managing injury and disease states with the Acoustic Coherent Tomography (ACT) imaging platform. With the ACT Platform, Decision Medical seeks to leverage the power of advanced coded wave forms, wide aperture imaging and Tomography to enable new possibilities for diagnosis, surgical planning, intraoperative guidance and postoperative monitoring.

Exogen, Inc. designs, develops, manufactures and markets medical devices for treatment of musculoskeletal injury and disease. The company's products include sonic acclerated fracture healing system and mechanical stress devices. The products are sold in the United States, Europe and Japan.

Chongqing Haifu (HIFU) Technology Co., Ltd. engages in the manufacture of medical devices for developing therapeutic ultrasound systems. It specializes in research, equipment development, manufacturing, clinical solutions, training support, marketing, and after-sales service of ultrasonic surgery. The company was founded on February 23, 1999 and is headquartered in Chongqing, China.

Olympic Ophthalmics is a medical device company developing novel treatments for dry eye disease. The company’s focus is to develop devices to treat the signs and symptoms of Dry Eye Disease (DED). It works by stimulating the trigeminal parasympathetic pathway to activate the glands responsible for tear film production. Olympic Ophthalmics was founded in 2017 by Michael Gertner and is based in Issaquah, Washington.

Otsuka Medical Devices, the holding company for Otsuka’s medical device operations, focuses on ‘minimally invasive’ and ‘innovative’ therapeutic devices. These include ultrasound-based renal denervation, drug-device combinations, and novel solutions targeted at drug-refractory patients and intractable diseases. Otsuka Medical Devices is an international group with a focus on Japan and Asia.

Assistance Publique des Hôpitaux de Paris SA the company is headquartered in Paris, France.

CLASSYS, Inc. engages in developing non-surgical electrotherapeutic devices. It offers electro medical and electrotherapeutic apparatus. The company was founded on January 15, 2015 and is headquartered in Seoul, South Korea.

Hitachi Healthcare Manufacturing Ltd. manufactures medical instruments, analyzers, and medical information systems. The company was founded on May 9, 1949 and is headquartered in Kashiwa, Japan.

LipoSonix, Inc. develops technology for non-invasive cosmetic surgery applications. Its products are used to remove fat and body sculpting. The company was founded by Steven B. Waite, Thomas D. Weldon, Jens Ulrich Quistgaard, Charles E. Larsen and John Arthur Deedrick in 1999 and is headquartered in Seattle, WA.

Novuson, a spinout from the University of Washington’s highly regarded Applied Physics Laboratory’s Center for Industrial and Medical Ultrasound, is developing its Direct Therapeutic Ultrasound (DTU) technology platform for coagulation and hemostatic control in surgical and trauma procedures. DTU technology should enable clinicians to perform surgeries more quickly and to rapidly control bleeding associated with traumatic injuries. The company founders are Stuart B. Mitchell, PhD. and Francesco P. Curra, Ph.D. Novuson creates tools that reduce operational cost and operating time, eliminating bleeding complications and enhancing patient outcomes. These automatic devices use direct therapeutic ultrasound energy for fast and robust hemostasis, cauterization and division. The devices cauterize tissue from the inside out, creating a well-defined, controlled plane of cauterization. The company was founded in 2014 and based in Bothell, Washington.

Siemens Medical Solutions USA, Inc. provides medical products and solutions. It offers imaging systems, therapy equipment, and hearing instruments for diagnosis, treatments, and patient monitoring. The firm services include imaging and therapy, customer resources and logins, healthcare financing solutions and laboratory diagnostics services. The company was founded in 1896 and is headquartered in Malvern, PA.

Part of Smith & Nephew plc, T.J. Smith & Nephew Ltd. is a British company located in Hull that manufactures healthcare products. It was founded in 1907. On July 01, 1999 Robinson Healthcare Group Ltd. acquired T.J. Smith & Nephew Ltd. from Smith & Nephew plc for $22.60 million.\nThe company says this about itself: The principal activity of the company is he design. development manufacture and sale of Advanced medical devices.

Sonablate Corp. develops and manufactures high intensity focused ultrasound surgical ablation systems. Its products include Sonablate 450, a HIFU solution that determines the safety and efficacy of a minimally invasive prostate cancer treatment; Sonablate 500, a HIFU surgical ablation system for the treatment of localized prostate cancer that delivers ablative therapy with the possibility of reducing side effects; and Sonatherm, a laparoscopic HIFU surgical ablation system that uses a laparoscopic probe to deliver robotic ablative therapy to soft tissue with a customizable ablation zone. The company was founded by Stephen R. Puckett Sr. and George M. Suarez in 2004 and is headquartered in Charlotte, NC.

Kona Medical is committed to alleviating the suffering and health risks associated with drug-resistant hypertension with a more effective, less invasive approach to renal artery denervation. The company was founded in 2009 by Michael Gertner, MD, with seed financing from Essex Woodlands. Kona was formed on the basis of combining Dr. Gertner’s inventions in the field with the assets of Therus Corporation, a predecessor company in the field of therapeutic focused ultrasound.