Blacksmith Medicines, Inc. is an American company located in San Diego, CA, with domestic subsidiaries. The firm develops medicines targeting metal-dependent enzymes found in human physiology. It was founded by Zachary A. Zimmerman, who is currently the CEO of the company.\nThe company says this about itself: At Blacksmith Medicines, we are developing medicines targeting metal-dependent enzymes. Over 30% of known enzymes are metalloenzymes, covering all major enzyme classes: oxidoreductases, transferases, hydrolases, lyases, isomerases, and ligases. Metal ions, including magnesium, zinc, iron, manganese and copper, are the essential ingredient in these metalloenzymes. We recognized a large unmet need for new chemical matter and innovative approaches to drug this important class of enzymes.