Iterion Therapeutics is a venture-backed, clinical-stage biotechnology company that develops novel targeted cancer therapeutics. The company’s lead product, Tegavivint, is a potent and selective inhibitor of the Wnt/b-catenin signaling pathway, implicated in cell proliferation, differentiation, immune evasion, and stem cell renewal. Tegavivint demonstrates pre-clinical in vivo efficacy in several cancer models including desmoid tumors, acute myeloid leukemia (AML), osteosarcoma, and a range of solid tumor types. The Company is currently enrolling a Phase I clinical study of Tegavivint in patients with desmoid tumors at multiple clinical centers in the United States and Canada. It was founded in 2010 and is headquartered in Houston, Texas.

Innoprot is a biotechnology company provider of Cell-Based Assays for drug discovery & development applications. Innoprot offers a wide range of stable cell lines and primary cells fully validated for High- Troughput Screening and High Content Screening. Stable cell lines developed by Innoprot are focused on drug discovery targeting mainly GPCRs, Nuclear hormone receptors, enzymes implicated in neurodegenerative diseases and ion channels. Innoprot has a proprietary technology for High Content Screening, which allow monitor changes in the concentrations of intracellular cAMP or Calcium by fluorescence imaging. Innoprot also offers custom assay development and High Content Screening Services, providing solutions to speed up the drug discovery campaigns of the customers.

Shanghai Bode Gene Development Co., Ltd., established on 1998-03-22, Business scope includes bioengineering,Technology transfer in the field of genetic engineering expertise,technology development,technical consulting,Technical services and manufacture of related reagents and equipment,Sales;Bioengineering and Genetic Engineering Products,electronics,Chemical Products(In addition to dangerous goods)import and export business. [Items subject to approval by law,Business activities can only be carried out after approval by relevant departments]

Shanghai Bodao Gene Technology Co., Ltd., established on 1998-12-17, Business scope includes bioengineering,Technology transfer in the field of genetic engineering,to develop,consult,Production, supply and marketing of services and related reagents and equipment. [Items subject to approval by law,Business activities can only be carried out after approval by relevant departments]

Shanghai Collison Biotechnology Co., Ltd., established on 2007-10-10, Business scope includes technology development in the field of biotechnology,technical consulting,Technical Services,technology transfer,Drug Discovery,laboratory reagent(In addition to dangerous goods),laboratory consumables,Pharmaceutical Intermediates(In addition to drugs),Chemical raw materials(Removal of hazardous chemicals,Monitor Chemicals,firecrackers,civilian explosives,precursor chemicals)promotion of,investment management,Business Information Consulting Service(In addition to brokerage),Hospital Investment Management,Medical device management. [Items subject to approval by law,Business activities can only be carried out after approval by relevant departments]

Axaron Bioscience AG is a German private company located in Heidelberg with domestic subsidiaries. The firm develops biotechnologies.

Caregen Co., Ltd. engages in the development of cosmetic products. Its products include products for professional therapy, home care products, food and beverages, and others. The company was founded on August 23, 2001 and is headquartered in Anyang-si, South Korea.

Cell Signaling Technology, Inc. (CST) is a privately held company that develops and produces antibodies, ELISA kits, ChIP kits, proteomic kits, and other related reagents used to study the cell signaling pathways that impact human health. CST maintains an in-house research program, particularly in the area of cancer research, and has published scientific papers in many peer-reviewed journals.

Develops and manufactures drugs related to immunology, neurobiology and oncology

Incyte Pharmaceuticals, Inc. engages in the provision of biopharmaceutical services. The company is headquartered in Palo Alto, CA.

Denka Corp., part of Denka Co., Ltd., is an American company located in New York, NY. The firm manufactures and distributes chemical products.

Trellis Bioscience develops a technology platform for cellular informatics. The company's technology has applications in the discovery and production of therapeutic monoclonal antibodies. Its cell biology platform provides a direct readout at the single cell level for monitoring activity of diverse cell types and quantifying the impact of potential therapeutic interventions. The company is based in San Francisco, California.

ITI Scotland Ltd. is a company set up in 2003 by Scottish Enterprise with the support of the Scottish Executive to identify and commercialise valuable technology-based intellectual assets across three global market sectors: digital media and communications; life sciences and energy.

Mogen International Nv, a subsidiary of AstraZeneca PLC, is a Dutch company located in Leiden involved in medicinal chemicals and botanical products. On May 01, 1997 Zeneca Group Plc acquired Mogen International Nv for $74.96 million.

Thermo Electron manufactures analytical instruments, equipment, reagents, consumables, and related services for a variety of domains. The company makes and distributes analytical instruments, equipment, and other laboratory supplies from chromatographs and spectrometers to Erlenmeyer flasks and fume hoods. It also provides specialty diagnostic testing products, as well as clinical analytical tools. Thermo Electron Corporation Pty. Ltd. is based in Elandsfontein, South Africa, and operates as a subsidiary of Thermo Fisher Scientific, Inc. The company was founded by George Hatsopoulos and was incorporated in 1956.

AstraZeneca is an innovation-driven biopharmaceutical company specializing in the discovery, development, manufacturing, and marketing of prescription medicines that make a meaningful difference in healthcare. AstraZeneca discovers new medicines that are designed to improve the health and quality of life of patients around the world - medicines that are innovative, effective, and which offer added benefits such as reduced side effects or better ways of taking the treatment. AstraZeneca focuses on getting the best from every medicine they make by exploring all the ways it can be used or improved. AstraZeneca was established on April 6, 1999, in Cambridgeshire, United Kingdom.

Incyte is a drug discovery and development company which hopes to build a proprietary product pipeline of novel small molecule drugs. Incyte's product pipeline is currently focused on oncology and inflammation and includes compounds in various stages of development. Through partnerships with [Novartis](/organization/novartis), [Eli Lilly](/organization/eli-lilly), and [Pfizer](/organization/pfizer), Incyte intends to promote the clinical development and global commercialization of several of their compounds.

Aurora Biosciences Corporation ("Aurora" or the "Company") designs and develops proprietary drug discovery systems, services and technologies to accelerate and enhance the discovery of new medicines. Aurora is developing an integrated technology platform comprised of a portfolio of proprietary fluorescent assay technologies and an ultra-high throughput screening ("UHTS") system designed to allow assay miniaturization and to overcome many of the limitations associated with the traditional drug discovery process.